Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | XPO1 | O14980 | 1/20 | 0.32 |
| ▸ | MYC | P01106 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8468242 | 0.85 | KDM4E (0.41) | MYCBRD4L3MBTL1ALDH1A1HPGD | |
| SCHEMBL8886696 | 0.84 | ALDH1A1 (0.38) | GRM1GRM4ESR1ESR2XPO1 | |
| SCHEMBL4845238 | 0.78 | MGLL (0.49) | ESR1ESR2ALDH1A1MAPTPKM | |
| SCHEMBL8886650 | 0.77 | POLB (0.42) | ESR1ESR2XPO1L3MBTL1ALDH1A1 | |
| SCHEMBL4846646 | 0.72 | MGLL (0.49) | ESR1ESR2ALDH1A1MAPTPKM | |
| SCHEMBL29999844 | 0.72 | POLB (0.57) | ALDH1A1MAPTPKMHPGDHSD17B10 | |
| SCHEMBL9073572 | 0.72 | POLB (0.57) | ALDH1A1MAPTPKMHPGDHSD17B10 | |
| Zinc Ion SCHEMBL31514063 | 0.72 | KDM4E (0.50) | BRD4L3MBTL1ALDH1A1HPGDHSD17B10 | |
| SCHEMBL8889997 | 0.71 | MYC (0.51) | MYCL3MBTL1ALDH1A1MAPTPKM | |
| Zinc Ion SCHEMBL6916339 | 0.69 | CYP1A2 (0.52) | ALDH1A1MAPTHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877327-A | METAL SALTS OF ITACONIMIDECARBOXYLIC ACIDS | AKZO NOBEL N.V. (NL) | 1999-03-02 | — | — | US | disclosed |
| EP-0638107-B1 | ANTI-FATIQUE COAGENTS FOR RUBBER VULCANIZATION | AKZO NOBEL NV (NL) | 1997-05-14 | — | — | EP | disclosed |
| US-5508354-A | Anti-fatigue coagents for rubber vulcanization | AKZO NOBEL N.V. (NL) | 1996-04-16 | — | — | US | disclosed |
| WO-1993022377-A1 | ANTI-FATIQUE COAGENTS FOR RUBBER VULCANIZATION | AKZO NOBEL N.V. (NL) | 1993-11-11 | — | — | WO | disclosed |