Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 12/20 | 0.49 |
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.35 |
| ▸ | CCR6 | P51684 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | G6PD | P11413 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4846646 | 0.93 | MGLL (0.49) | MGLLTLR9FAAHALDH1A1PKM | |
| SCHEMBL8886696 | 0.93 | ALDH1A1 (0.38) | MGLLTLR9ALDH1A1PKMMAPT | |
| SCHEMBL2229804 | 0.88 | TLR9 (0.63) | MGLLTLR9FAAHALDH1A1PKM | |
| SCHEMBL8886650 | 0.86 | POLB (0.42) | MGLLTLR9ALDH1A1PKMMAPT | |
| SCHEMBL31180023 | 0.82 | TLR9 (0.68) | MGLLTLR9FAAHALDH1A1PKM | |
| SCHEMBL5077484 | 0.82 | TLR9 (0.68) | MGLLTLR9FAAHALDH1A1PKM | |
| SCHEMBL2230828 | 0.81 | MGLL (0.50) | MGLLTLR9FAAHALDH1A1PKM | |
| SCHEMBL29999844 | 0.80 | POLB (0.57) | MGLLALDH1A1PKMMAPTHPGD | |
| SCHEMBL9073572 | 0.80 | POLB (0.57) | MGLLALDH1A1PKMMAPTHPGD | |
| SCHEMBL7193393 | 0.80 | TLR9 (0.48) | MGLLTLR9FAAHPKMMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7442733-B2 | Rubber composition comprising a citraconimidomaleimide | MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) | 2008-10-28 | — | — | US | disclosed |
| US-20060247342-A1 | Rubber composition comprising a citraconimidomaleimide | MICHELIN RECHERCHE ET TECHNIQUE S.A. | 2006-11-02 | — | — | US | disclosed |
| EP-1664180-A1 | RUBBER COMPOSITION COMPRISING A CITRACONIMIDO-MALEIMIDE | Société de Technologie Michelin (FR) | 2006-06-07 | — | — | EP | disclosed |
| WO-2005026250-A1 | RUBBER COMPOSITION COMPRISING A CITRACONIMIDO-MALEIMIDE | SOCIETE DE TECHNOLOGIE MICHELIN (FR) | 2005-03-24 | — | — | WO | disclosed |