SCHEMBL8889997

SCHEMBL8889997

CC1=CC(=O)N(c2ccccc2C(=O)O)C1=O

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MYC P01106 4/20 0.51
NR4A1 P22736 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.49
GAA P10253 2/20 0.49
APEX1 P27695 2/20 0.48
ALDH1A1 P00352 4/20 0.45
ALOX15 P16050 1/20 0.45
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 3/20 0.44
HSP90AA1 P07900 1/20 0.44
PKM P14618 1/20 0.44
CCR6 P51684 1/20 0.44
ATM Q13315 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
TLR9 Q9NR96 1/20 0.44
POLB P06746 2/20 0.42
MEN1 O00255 3/20 0.40
KMT2A Q03164 3/20 0.40
MAPT P10636 1/20 0.40
AKR1C3 P42330 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9547473 0.85 TYMS (0.46) MYCNR4A1L3MBTL1GAAAPEX1
SCHEMBL8443589 0.83 ALDH1A1 (0.36) MYCNR4A1L3MBTL1GAAAPEX1
SCHEMBL8468242 0.81 KDM4E (0.41) MYCNR4A1L3MBTL1GAAAPEX1
SCHEMBL8889877 0.80 MYC (0.58) MYCNR4A1L3MBTL1GAAAPEX1
Hydrochloric Acid SCHEMBL7461209 0.78 MYC (0.56) MYCNR4A1L3MBTL1GAAAPEX1
SCHEMBL30473083 0.78 MGLL (0.60) L3MBTL1ALDH1A1ALOX15TSHRTDP1
SCHEMBL2229804 0.76 TLR9 (0.63) ALDH1A1TSHRTDP1HSP90AA1PKM
SCHEMBL183052 0.75 ALDH1A1 (0.71) MYCNR4A1L3MBTL1GAAAPEX1
SCHEMBL29364136 0.75 ALDH1A1 (0.71) MYCNR4A1L3MBTL1GAAAPEX1
SCHEMBL20261770 0.75 MGLL (0.59) GAATSHRPKMTLR9MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0336856-B1 WITH MALEIMIDE GROUPS FUNCTIONALIZED AROMATIC POLYAMIDEIMIDES, PROCESS FOR THEIR PREPARATION AND THEIR USE FOR PREPARING CROSS-LINKED POLYMERS CIBA-GEIGY AG (CH) 1993-03-03 EP claimed
US-4927900-A Aromatic polyamidoimides having maleimido end groups RHONE-POULENC CHIMIE (FR) 1990-05-22 US claimed
WO-1997003962-A1 IMIDO PERESTERS AS INITIATORS OF POLYMERIZATION PROCESSES AKZO NOBEL N.V. (NL) 1997-02-06 WO disclosed
US-5470920-A Impregnating solutions based on at least one reactive thermoplastic poly (imide-amide) oligomer and a coreactant, which can be used especially for the production of preimpregnated intermediate articles CIBA-GEIGY CORPORATION (US) 1995-11-28 US disclosed
US-4927900-A Aromatic polyamidoimides having maleimido end groups RHONE-POULENC CHIMIE (FR) 1990-05-22 US disclosed