SCHEMBL8468246

SCHEMBL8468246

COC(=O)C1CCC(CCCC=O)C1=O

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.32
CYP1A2 P05177 1/20 0.32
HIF1A Q16665 1/20 0.32
OPRK1 P41145 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8859120 0.81 FAAH (0.35) FAAH
SCHEMBL11770967 0.80 FKBP1A (0.36) CYP1A2HIF1A
SCHEMBL5896745 0.76 CYP1A2 (0.38) CYP1A2HIF1A
SCHEMBL6823417 0.75 SLC6A4 (0.43)
SCHEMBL11652834 0.74 CYP1A2 (0.34) CYP1A2HIF1A
SCHEMBL13882832 0.73 CYP1A2 (0.46) CYP1A2HIF1A
SCHEMBL30052789 0.68 BRD4 (0.36) CYP1A2HIF1A
SCHEMBL17065544 0.68 ALDH1A1 (0.49) CYP1A2
SCHEMBL5346726 0.67 CYP1A2 (0.41) CYP1A2HIF1A
SCHEMBL9511515 0.66 TSHR (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5973080-A MODIFIED DIVINYLBENZENE-STYRENE COPOLYMER ELF AQUITAINE PRODUCTION (FR) 1999-10-26 US disclosed
US-5817716-A MODIFIED DIVINYLBENZENE-STYRENE COPOLYMER ELF AQUITAINE PRODUCTION (FR) 1998-10-06 US disclosed
US-5726253-A REACTING DIVINYLBENZENE-STYRENE RESIN WITH CHLOROFORMAMIDINIUM CHLORIDE IN BASE ELF AQUITAINE PRODUCTION (FR) 1998-03-10 US disclosed