Bilirubin

Bilirubin

SCHEMBL8468334

C=CC1=C(C)/C(=C/c2[nH]c(Cc3[nH]c(/C=C4\NC(=O)C(C)=C4C=C)c(C)c3CCC(=O)O)c(CCC(=O)O)c2C)NC1=O.[NaH]

nearest known ligand 0.98

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.98
MEN1 O00255 1/20 0.98
ALDH1A1 P00352 1/20 0.98
LMNA P02545 1/20 0.98
MAPT P10636 1/20 0.98
CASP1 P29466 1/20 0.98
CASP7 P55210 1/20 0.98
KMT2A Q03164 1/20 0.98
HSD17B10 Q99714 1/20 0.98
SLCO1B3 Q9NPD5 1/20 0.98
TDP1 Q9NUW8 1/20 0.98
SLCO1B1 Q9Y6L6 1/20 0.98
P2RX7 Q99572 1/20 0.90
ABCC1 P33527 2/20 0.70
ABCC2 Q92887 2/20 0.70
KDR P35968 13/20 0.38
FGFR1 P11362 12/20 0.38
PDGFRB P09619 11/20 0.38
FLT3 P36888 3/20 0.38
AURKB Q96GD4 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bilirubin SCHEMBL11412908 1.00 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL10565617 0.99 KDM4E (1.00) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL3361472 0.99 KDM4E (1.00) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL5086205 0.99 KDM4E (1.00) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL19065 0.99 KDM4E (1.00) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL32671479 0.99 KDM4E (1.00) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL23529823 0.98 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL5493673 0.98 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL2942018 0.98 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL9116171 0.98 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117986181-A Preparation method of high-purity bilirubin sodium ditaurin 长春百纯和成医药科技有限公司 2024-05-07 CN claimed
CN-117143001-A Method for recovering high-purity bilirubin 帅放文 2023-12-01 CN claimed
CN-113049839-B Stable liver function composite quality control product 桂林英美特生物技术研究所 2022-11-29 CN claimed
CN-113049839-A Stable liver function composite quality control product 桂林英美特生物技术研究所 2021-06-29 CN claimed
CN-108295065-A A kind of calculus bovis factitius preparation method 重庆芸峰药业有限公司 2018-07-20 CN claimed
CN-105399655-A Preparation method and application of sodium bilirubin ZHANG HENGZHOU 2016-03-16 CN claimed
CN-117986181-A Preparation method of high-purity bilirubin sodium ditaurin 长春百纯和成医药科技有限公司 2024-05-07 CN disclosed
CN-117986181-A Preparation method of high-purity bilirubin sodium ditaurin 长春百纯和成医药科技有限公司 2024-05-07 CN disclosed
CN-117986181-A Preparation method of high-purity bilirubin sodium ditaurin 长春百纯和成医药科技有限公司 2024-05-07 CN disclosed
CN-117843546-A Bilirubin extraction method 四川菲德力制药有限公司 2024-04-09 CN disclosed
CN-117143001-A Method for recovering high-purity bilirubin 帅放文 2023-12-01 CN disclosed
CN-116211258-A Jaundice detection patch based on organic photoelectric detector, system and preparation method 清华大学深圳国际研究生院 2023-06-06 CN disclosed
EP-3399959-B1 COMPOSITION TO IMPROVE METABOLIC AND VASCULAR HEALTH AND HEALTH SPAN THORNALLEY PAUL JOHN (GB) 2023-05-24 EP disclosed
CN-104774885-A Method for extracting bilirubin from ox bile by using fermentation process WUHAN JIANMIN DAPENG PHARMACEUTICAL CO LTD 2015-07-15 CN disclosed
CN-102229556-B Method for producing bilirubin HEPARINTECH SICHUAN CO LTD 2013-04-17 CN disclosed
CN-102229556-A Method for producing bilirubin HEPARINTECH SICHUAN CO LTD 2011-11-02 CN disclosed
CN-102127000-A Method for extracting high purity bilirubin from low purity bilirubin WUHAN DAPENG PHARMACEUTICAL CO LTD 2011-07-20 CN disclosed
US-5928645-A EXTRACT CONTAINING BERBERINE AND A FLAVONOID YOUNG BOK HAN & KOREAN ASSOC. OF CREATION RESEARCH (KR) 1999-07-27 US disclosed
CN-1042908-A The bilirubinic method of high-content rapid extraction CAO HEYANG (CN) 1990-06-13 CN disclosed
CN-1042908-A The bilirubinic method of high-content rapid extraction CAO HEYANG (CN) 1990-06-13 CN disclosed