Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | CASP1 | P29466 | 1/20 | 1.00 |
| ▸ | CASP7 | P55210 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 1.00 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.92 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.71 |
| ▸ | ABCC2 | Q92887 | 2/20 | 0.71 |
| ▸ | KDR | P35968 | 13/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 12/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 11/20 | 0.38 |
| ▸ | FLT3 | P36888 | 3/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bilirubin SCHEMBL32671479 | 1.00 | KDM4E (1.00) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL5086205 | 1.00 | KDM4E (1.00) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL10565617 | 1.00 | KDM4E (1.00) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL19065 | 1.00 | KDM4E (1.00) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL23529823 | 0.99 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL5493673 | 0.99 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL11412908 | 0.99 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL8468334 | 0.99 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL2942018 | 0.99 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL9116171 | 0.99 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023010752-A1 | MARKER, DETECTION METHOD, AND KIT FOR EVALUATING CARDIAC INJURY OF SCHIZOPHRENIA PATIENT | 中国科学院深圳先进技术研究院 | 2023-02-09 | — | — | WO | disclosed |
| EP-4106776-A1 | METHOD FOR TREATING CHRONIC GRAFT VERSUS HOST DISEASE | Mesoblast International Sàrl (CH) | 2022-12-28 | — | — | EP | disclosed |
| CN-107446034-B | Fluorescent protein probes and preparation method and application thereof | 华东理工大学 | 2021-05-14 | — | — | CN | disclosed |
| WO-2020194830-A1 | URINALYSIS DEVICE AND HEALTH FACILITATION SYSTEM | 株式会社ファーストスクリーニング | 2020-10-01 | — | — | WO | disclosed |
| WO-2019187018-A1 | HEALTH FACILITATION SYSTEM, SENSOR, AND HEALTH FACILITATION METHOD | 株式会社ファーストスクリーニング | 2019-10-03 | — | — | WO | disclosed |
| EP-3436813-A1 | WATER-ABSORBING MATERIAL AND USES THEREOF | 7905122 Canada Inc. (CA) | 2019-02-06 | — | — | EP | disclosed |
| CN-109081798-A | A kind of preparation method of high-purity bilirubin | 中国计量科学研究院 | 2018-12-25 | — | — | CN | disclosed |
| WO-2017165953-A1 | WATER-ABSORBING MATERIAL AND USES THEREOF | 7905122 CANADA INC. (CA) | 2017-10-05 | — | — | WO | disclosed |
| CN-103463578-B | Medicament for treating cholelithiasis, cholecystitis and hyperbilirubinemia | WANG ZIDONG | 2015-04-29 | — | — | CN | disclosed |
| CN-104324089-A | Rhubarb total anthraquinone being stable and uniform in proportion of various components and composition thereof used in jaundice-eliminating treatment of viral hepatitis type B | JIANGXI BAISHEN CHANGNUO PHARMACEUTICAL CO LTD | 2015-02-04 | — | — | CN | disclosed |
| EP-0874984-A1 | ELECTROCHEMICAL BIOSENSOR TEST STRIP | BOEHRINGER MANNHEIM CORPORATION (US) | 1998-11-04 | — | — | EP | disclosed |
| CN-1162264-A | Use of corticosteroid to reduce adverse effects of perfluorochemical emulsion | HEMAGEN PFC (US) | 1997-10-15 | — | — | CN | disclosed |
| WO-1997002487-A1 | ELECTROCHEMICAL BIOSENSOR TEST STRIP | BOEHRINGER MANNHEIM CORPORATION (US) | 1997-01-23 | — | — | WO | disclosed |
| US-5559003-A | BILIRUBIN INTERFERENCE | DAIICHI PURE CHEMICALS CO., LTD. (JP) | 1996-09-24 | — | — | US | disclosed |
| EP-0505494-A4 | REDOX MEDIATOR REAGENT AND BIOSENSOR | — | 1993-10-06 | — | — | EP | disclosed |
| EP-0505494-A1 | REDOX MEDIATOR REAGENT AND BIOSENSOR. | BOEHRINGER MANNHEIM CORP (US) | 1992-09-30 | — | — | EP | disclosed |
| WO-1991009139-A1 | REDOX MEDIATOR REAGENT AND BIOSENSOR | BOEHRINGER MANNHEIM CORPORATION (US) | 1991-06-27 | — | — | WO | disclosed |
| US-4892833-A | BILIRUBIN, COUPLING WITH DIAZONIUM SALT, BUFFER | BOEHRINGER MANNHEIM GMBH (DE) | 1990-01-09 | — | — | US | disclosed |
| US-4584197-A | DECOMPOSING WITH BACILLUS AND KOJI PROTEINASES | NIHON BUSSAN KABUSHIKI KAISHA (JP) | 1986-04-22 | — | — | US | disclosed |
| US-4274832-A | Analytical element and method for analysis of multiple analytes | EASTMAN KODAK COMPANY (US) | 1981-06-23 | — | — | US | disclosed |