Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 1.00 |
| ▸ | MEN1 | O00255 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 1.00 |
| ▸ | LMNA | P02545 | 1/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | CASP1 | P29466 | 1/20 | 1.00 |
| ▸ | CASP7 | P55210 | 1/20 | 1.00 |
| ▸ | KMT2A | Q03164 | 1/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 1.00 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 1.00 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 1.00 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 1.00 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.92 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.71 |
| ▸ | ABCC2 | Q92887 | 2/20 | 0.71 |
| ▸ | KDR | P35968 | 13/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 12/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 11/20 | 0.38 |
| ▸ | FLT3 | P36888 | 3/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bilirubin SCHEMBL32671479 | 1.00 | KDM4E (1.00) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL3361472 | 1.00 | KDM4E (1.00) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL10565617 | 1.00 | KDM4E (1.00) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL19065 | 1.00 | KDM4E (1.00) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL23529823 | 0.99 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL5493673 | 0.99 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL11412908 | 0.99 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL8468334 | 0.99 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL2942018 | 0.99 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL9116171 | 0.99 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1481700-B1 | Device for extracorporeal irradiation of a liquid containing bilirubin | FRESENIUS MEDICAL CARE DE GMBH (DE) | 2014-01-22 | — | — | EP | disclosed |
| US-7846121-B2 | Device for extracorporeal irradiation of a liquid containing bilirubin, and method therefor | Fresenious Medical Care Deutschland GmbH (DE) | 2010-12-07 | — | — | US | disclosed |
| US-20080070971-A1 | Medical Use of Bilirubin and its Structural Analogues | WANG XIANG H | 2008-03-20 | — | — | US | disclosed |
| US-20080070971-A1 | Medical Use of Bilirubin and its Structural Analogues | WANG XIANG H | 2008-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080070971-A1 | Medical Use of Bilirubin and its Structural Analogues | RBP1, RBP4, AGER | KDM4E 3579/4885MEN1 2977/4885ALDH1A1 1190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.