Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.98 |
| ▸ | MEN1 | O00255 | 1/20 | 0.98 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.98 |
| ▸ | LMNA | P02545 | 1/20 | 0.98 |
| ▸ | MAPT | P10636 | 1/20 | 0.98 |
| ▸ | CASP1 | P29466 | 1/20 | 0.98 |
| ▸ | CASP7 | P55210 | 1/20 | 0.98 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.98 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.98 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.98 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.98 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.98 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.90 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.70 |
| ▸ | ABCC2 | Q92887 | 2/20 | 0.70 |
| ▸ | KDR | P35968 | 13/20 | 0.38 |
| ▸ | FGFR1 | P11362 | 12/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 11/20 | 0.38 |
| ▸ | FLT3 | P36888 | 3/20 | 0.38 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bilirubin SCHEMBL3361472 | 0.99 | KDM4E (1.00) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL10565617 | 0.99 | KDM4E (1.00) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL5086205 | 0.99 | KDM4E (1.00) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL19065 | 0.99 | KDM4E (1.00) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL32671479 | 0.99 | KDM4E (1.00) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL23529823 | 0.98 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL5493673 | 0.98 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL11412908 | 0.98 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL6735045 | 0.98 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT | |
| Bilirubin SCHEMBL9116171 | 0.98 | KDM4E (0.98) | KDM4EMEN1ALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3010556-B1 | MATRIX AND IMPLANT FOR TISSUE ENGINEERING | BAER HANS U (CH) | 2019-01-30 | — | — | EP | disclosed |
| EP-2815773-B1 | Matrix and implant for tissue engineering | BAER HANS U (CH) | 2017-08-30 | — | — | EP | disclosed |
| US-20160130558-A1 | MATRIX AND IMPLANT FOR TISSUE ENGINEERING | BAER HANS U (CH) | 2016-05-12 | — | — | US | disclosed |
| EP-3010556-A1 | MATRIX AND IMPLANT FOR TISSUE ENGINEERING | Baer, Hans U. (CH) | 2016-04-27 | — | — | EP | disclosed |
| WO-2014202199-A1 | MATRIX AND IMPLANT FOR TISSUE ENGINEERING | BAER HANS U (CH) | 2014-12-24 | — | — | WO | disclosed |
| EP-2815773-A1 | Matrix and implant for tissue engineering | Baer, Hans U. (CH) | 2014-12-24 | — | — | EP | disclosed |
| US-8344019-B2 | Methods for the production of biliverdin | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2013-01-01 | — | — | US | disclosed |
| US-8309115-B2 | Matrix, cell implantation and method for their production and use | HUMANAUTOCELL GMBH (DE) | 2012-11-13 | — | — | US | disclosed |
| US-20120142751-A1 | METHODS FOR THE PRODUCTION OF BILIVERDIN | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF (US) | 2012-06-07 | — | — | US | disclosed |
| US-20100028405-A1 | MATRIX, CELL IMPLANTATION AND METHOD FOR THEIR PRODUCTION AND USE | HUMANAUTOCELL GMBH (DE) | 2010-02-04 | — | — | US | disclosed |
| US-7618646-B2 | Matrix, cell implant and method for their production and use | HUMANAUTOCELL GMBH (DE) | 2009-11-17 | — | — | US | disclosed |
| US-20090203762-A1 | METHODS FOR THE PRODUCTION OF BILIVERDIN | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPT. OF HEALTH AND HUMAN SERVICES | 2009-08-13 | — | — | US | disclosed |
| US-7504243-B2 | Methods for the production of biliverdin | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2009-03-17 | — | — | US | disclosed |
| US-20070166343-A1 | Matrix, cell implantation and method for their production and use | HUMANAUTOCELL GMBH (DE) | 2007-07-19 | — | — | US | disclosed |
| US-20050209305-A1 | Methods for the production of biliverdin | PENDRAK MICHAEL L | 2005-09-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070166343-A1 | Matrix, cell implantation and method for their production and use | IAPP, MMP1, CD68 | KDM4E 3891/4885MEN1 646/4885ALDH1A1 2195/4885 |
| US-20100028405-A1 | MATRIX, CELL IMPLANTATION AND METHOD FOR THEIR PRODUCTION AND USE | IAPP, MMP1, CD68 | KDM4E 3891/4885MEN1 646/4885ALDH1A1 2195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.