Bilirubin

Bilirubin

SCHEMBL19065

C=CC1=C(C)/C(=C/c2[nH]c(Cc3[nH]c(/C=C4\NC(=O)C(C)=C4C=C)c(C)c3CCC(=O)O)c(CCC(=O)O)c2C)NC1=O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 1.00
MEN1 O00255 1/20 1.00
ALDH1A1 P00352 1/20 1.00
LMNA P02545 1/20 1.00
MAPT P10636 1/20 1.00
CASP1 P29466 1/20 1.00
CASP7 P55210 1/20 1.00
KMT2A Q03164 1/20 1.00
HSD17B10 Q99714 1/20 1.00
SLCO1B3 Q9NPD5 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
SLCO1B1 Q9Y6L6 1/20 1.00
P2RX7 Q99572 1/20 0.92
ABCC1 P33527 2/20 0.71
ABCC2 Q92887 2/20 0.71
KDR P35968 13/20 0.38
FGFR1 P11362 12/20 0.38
PDGFRB P09619 11/20 0.38
FLT3 P36888 3/20 0.38
AURKB Q96GD4 3/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bilirubin SCHEMBL32671479 1.00 KDM4E (1.00) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL5086205 1.00 KDM4E (1.00) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL3361472 1.00 KDM4E (1.00) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL10565617 1.00 KDM4E (1.00) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL23529823 0.99 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL5493673 0.99 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL11412908 0.99 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL8468334 0.99 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL2942018 0.99 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT
Bilirubin SCHEMBL9116171 0.99 KDM4E (0.98) KDM4EMEN1ALDH1A1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 116924 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260148866-A1 MACHINE LEARNING SYSTEMS AND RELATED ASPECTS FOR CLASSIFYING INDETERMINATE BILIARY STRICTURES THE JOHNS HOPKINS UNIVERSITY (US) 2026-05-28 US claimed
EP-4747607-A1 DEVICES AND METHODS FOR OPTICAL ANALYSIS OF BIOLOGICAL SAMPLES Vital Biosciences Inc. (CA) 2026-05-27 EP claimed
EP-4747627-A1 METHODS AND SYSTEMS FOR PREDICTIVE CLASSIFICATION BY MASS SPECTROMETRY AND TRAINED LARGE SPECTRAL MODELS Matterworks Inc (US) 2026-05-27 EP claimed
CN-122081442-A Fingertip peripheral blood lipid multi-index synchronous analysis method and system 2026-05-26 CN claimed
US-12638463-B2 Analysis of bodily emissons OUTSENSE DIAGNOSTICS LTD. (IL) 2026-05-26 US claimed
CN-122075484-A Application of melatonin in bilirubin encephalopathy anti-inflammatory intervention 2026-05-26 CN claimed
CN-122094690-A Pharmaceutical composition comprising Maraglinib (MARALIXIBAT) and use thereof 2026-05-26 CN claimed
US-12635894-B2 Sensor device to mitigate the effects of unwanted signals made in optical measurements of biological properties Biobeat Technologies Ltd. (IL) 2026-05-26 US claimed
WO-2026107292-A1 FEED ADDITIVE COMPOSITIONS AND METHODS FOR MAKING AND USING THE SAME CAN TECHNOLOGIES, INC. (US) 2026-05-21 WO claimed
WO-2026102485-A1 PRODUCTS AND METHODS FOR THE ASSESSMENT AND TREATMENT OF SEPSIS AND IMMUNOLOGICAL AND INFLAMMATORY CONDITIONS CENTRAL ADELAIDE LOCAL HEALTH NETWORK INC (AU) 2026-05-21 WO claimed
US-4062713-A Photodosimeter film badge BECKMAN INSTRUMENTS, INC. (US) 1977-12-13 US claimed
US-4056357-A Direct bilirubin assay TECHNICON INSTRUMENTS CORPORATION (US) 1977-11-01 US claimed
US-4046514-A TEST DEVICE AND METHOD FOR DETERMINING A COMPONENT IN A SAMPLE MILES LABORATORIES, INC. (US) 1977-09-06 US claimed
US-4038485-A TEST COMPOSITION, DEVICE, AND METHOD MILES LABORATORIES, INC. (US) 1977-07-26 US claimed
US-4038031-A REACTION WITH DIAZONIUM COMPOUND MILES LABORATORIES, INC. (US) 1977-07-26 US claimed
US-4030885-A COLORIMETRIC ANALYSIS SIGMA CHEMICAL COMPANY (US) 1977-06-21 US claimed
US-4029085-A Method for determining bilirubin concentration from skin reflectance PURDUE RESEARCH FOUNDATION (US) 1977-06-14 US claimed
US-4019961-A MULTISTAGE; NADH-REGENERATING SYSTEM BOEHRINGER MANNHEIM G.M.B.H. (DT) 1977-04-26 US claimed
US-3980696-A Photodosimeter film badge BECKMAN INSTRUMENTS, INC. (US) 1976-09-14 US claimed
US-3951796-A Oil recirculating toilets MONOGRAM INDUSTRIES, INC. (US) 1976-04-20 US claimed