Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 12/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6941606 | 0.96 | PTPN1 (0.41) | PTPN1HPGDPOLBALOX12KDM4E | |
| SCHEMBL6937953 | 0.90 | GPR84 (0.40) | PTPN1HPGDPOLBALOX12MAPT | |
| SCHEMBL9064640 | 0.80 | ALDH1A1 (0.55) | HPGDPOLBALOX12MEN1KMT2A | |
| SCHEMBL8887852 | 0.80 | ALDH1A1 (0.34) | HPGDPOLBALOX12MEN1KMT2A | |
| SCHEMBL7469680 | 0.79 | PTPN1 (0.42) | PTPN1HPGDPOLBALOX12MEN1 | |
| Hydrochloric Acid SCHEMBL7462193 | 0.77 | PTPN1 (0.41) | PTPN1HPGDPOLBALOX12MEN1 | |
| SCHEMBL9064577 | 0.76 | ALDH1A1 (0.40) | HPGDPOLBALOX12MEN1KMT2A | |
| SCHEMBL43970 | 0.76 | PTPN1 (0.42) | PTPN1HPGDPOLBALOX12KDM4E | |
| Hydrochloric Acid SCHEMBL4277446 | 0.74 | PTPN1 (0.41) | PTPN1HPGDPOLBALOX12KDM4E | |
| SCHEMBL6939678 | 0.73 | GPR84 (0.46) | PTPN1HPGDPOLBALOX12MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5877327-A | METAL SALTS OF ITACONIMIDECARBOXYLIC ACIDS | AKZO NOBEL N.V. (NL) | 1999-03-02 | — | — | US | disclosed |
| EP-0638107-B1 | ANTI-FATIQUE COAGENTS FOR RUBBER VULCANIZATION | AKZO NOBEL NV (NL) | 1997-05-14 | — | — | EP | disclosed |
| US-5508354-A | Anti-fatigue coagents for rubber vulcanization | AKZO NOBEL N.V. (NL) | 1996-04-16 | — | — | US | disclosed |
| WO-1993022377-A1 | ANTI-FATIQUE COAGENTS FOR RUBBER VULCANIZATION | AKZO NOBEL N.V. (NL) | 1993-11-11 | — | — | WO | disclosed |