Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | PPM1B | O75688 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9064577 | 0.84 | ALDH1A1 (0.40) | ALDH1A1MAPK1KDM4EHPGDHSD17B10 | |
| SCHEMBL6941606 | 0.83 | PTPN1 (0.41) | ALDH1A1MAPK1KDM4EHPGDHSD17B10 | |
| SCHEMBL6937953 | 0.81 | GPR84 (0.40) | ALDH1A1MAPK1KDM4EHPGDHSD17B10 | |
| SCHEMBL8468436 | 0.80 | PTPN1 (0.39) | ALDH1A1MAPK1KDM4EHPGDHSD17B10 | |
| SCHEMBL8835130 | 0.76 | KDM4E (0.60) | ALDH1A1MAPK1KDM4EHPGDHSD17B10 | |
| SCHEMBL411116 | 0.74 | ALDH1A1 (0.58) | ALDH1A1MAPK1KDM4EHPGDHSD17B10 | |
| SCHEMBL9064507 | 0.73 | CSNK2A2 (0.46) | ALDH1A1KDM4EHPGDHSD17B10POLB | |
| SCHEMBL18137235 | 0.73 | MAPK1 (0.49) | ALDH1A1MAPK1KDM4EHPGDHSD17B10 | |
| SCHEMBL14991107 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MAPK1KDM4EHPGDHSD17B10 | |
| SCHEMBL441970 | 0.71 | ALDH1A1 (1.00) | ALDH1A1MAPK1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5523360-A | IMPROVES MELT-FLOW PROPERTIES | AKZO NOBEL N. V. (NL) | 1996-06-04 | — | — | US | disclosed |
| EP-0648240-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | Akzo Nobel N.V. (NL) | 1995-04-19 | — | — | EP | disclosed |
| WO-1994001485-A1 | PROCESS FOR THE MODIFICATION OF POLYPHENYLENE ETHER RESIN COMPOSITIONS | AKZO NOBEL N.V. (NL) | 1994-01-20 | — | — | WO | disclosed |