Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | CASP6 | P55212 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8668081 | 0.78 | ALDH1A1 (0.36) | HTTALDH1A1MAPTLMNAPOLB | |
| SCHEMBL19952852 | 0.78 | IMPDH2 (0.41) | HTTALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL11236385 | 0.78 | ALDH1A1 (0.39) | ALDH1A1MAPTNPC1LMNATP53 | |
| SCHEMBL5135211 | 0.75 | GABRA1 (0.35) | POLBGABRA1GABRB2 | |
| SCHEMBL11442960 | 0.74 | POLB (0.44) | HTTALDH1A1MAPTLMNASMN1; SMN2 | |
| SCHEMBL11077537 | 0.73 | MAPT (0.45) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| SCHEMBL9244533 | 0.73 | GABRA1 (0.34) | POLBGABRA1GABRB2 | |
| SCHEMBL7783997 | 0.72 | GABRA1 (0.44) | ALDH1A1MAPTHPGDPOLBMEN1 | |
| SCHEMBL8598691 | 0.71 | IMPDH2 (0.32) | ALDH1A1MAPTPOLBMEN1GAA | |
| SCHEMBL1644916 | 0.70 | CYP3A4 (0.51) | HTTALDH1A1MAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0852005-A4 | COMPETITIVE IMMUNOASSAY DEVICE | SMITHKLINE DIAGNOSTICS INC (US) | 1999-06-09 | — | — | EP | disclosed |
| EP-0852005-A1 | COMPETITIVE IMMUNOASSAY DEVICE | SMITHKLINE DIAGNOSTICS, INC. (US) | 1998-07-08 | — | — | EP | disclosed |
| WO-1996038720-A1 | COMPETITIVE IMMUNOASSAY DEVICE | SMITHKLINE DIAGNOSTICS, INC. (US) | 1996-12-05 | — | — | WO | disclosed |