SCHEMBL8468796

SCHEMBL8468796

C=CC(=O)[Si](OCCOC)(OCCOC)OCCOC

nearest known ligand 0.31

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 6/20 0.31
HPGD P15428 1/20 0.31
ALDH1A1 P00352 4/20 0.30
TP53 P04637 2/20 0.30
HIF1A Q16665 2/20 0.30
CYP3A4 P08684 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15212537 0.81 TSHR (0.41) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL2843011 0.76 ALDH1A1 (0.39) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL1724859 0.72 ALDH1A1 (0.38) TSHRALDH1A1
Acrylic Acid SCHEMBL26134427 0.72 LMNA (0.56) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL5700760 0.71 CYP3A4 (0.32) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL28028849 0.71 TSHR (0.34) TSHRHPGDALDH1A1
SCHEMBL25189741 0.70 FFAR3 (0.33) TSHRALDH1A1
SCHEMBL230526 0.69 TSHR (0.43) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL229899 0.68 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A
SCHEMBL227221 0.68 TSHR (0.42) TSHRHPGDALDH1A1TP53HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110573964-B Negative photosensitive resin composition and cured film 东丽株式会社 2023-11-03 CN disclosed
US-5908899-A RUBBER-MODIFIED UNSATURATED COMPOUND OBTAINED BY GRAFTING A MONOMER HAVING AT LEAST ONE POLYMERIZABLE ETHYLENICALLY UNSATURATED BOND IN A MOLECULE WITH AT LEAST ONE RUBBER; A COUPLING AGENT, A FILLER AND A PHOTOPOLYMERIZATION INITIATOR. MITSUI CHEMICALS, INC. (JP) 1999-06-01 US disclosed