Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29991977 | 0.83 | LMNA (0.40) | ESR1ESR2TP53ALDH1A1HPGD | |
| SCHEMBL29992598 | 0.80 | TSHR (0.34) | ESR1ESR2TP53KDM4EALDH1A1 | |
| SCHEMBL2274337 | 0.77 | ESR1 (0.37) | ESR1ESR2TP53KDM4EALDH1A1 | |
| SCHEMBL22444885 | 0.75 | LTA4H (0.31) | TP53KDM4EALDH1A1LTA4HNCF1 | |
| SCHEMBL2329848 | 0.74 | NR1H2 (0.47) | ESR1ESR2TP53KDM4EALDH1A1 | |
| Ether SCHEMBL28645485 | 0.71 | LTA4H (0.34) | ESR1ESR2TP53KDM4EALDH1A1 | |
| Ether SCHEMBL28930315 | 0.71 | LTA4H (0.34) | ESR1ESR2TP53KDM4EALDH1A1 | |
| SCHEMBL8341054 | 0.71 | ESR1 (0.32) | ESR1ESR2TP53KDM4EALDH1A1 | |
| SCHEMBL20637319 | 0.70 | ESR1 (0.38) | ESR1ESR2TP53KDM4EALDH1A1 | |
| SCHEMBL17654203 | 0.69 | SMN1; SMN2 (0.49) | TP53KDM4EALDH1A1SMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433296-B | Catalyst composition and application thereof in olefin polymerization | 中国科学院化学研究所 | 2024-04-05 | — | — | CN | claimed |
| CN-115433296-B | Catalyst composition and application thereof in olefin polymerization | 中国科学院化学研究所 | 2024-04-05 | — | — | CN | disclosed |
| CN-115433221-A | Bis (alkoxyalkyl) silane external electron donor, preparation method thereof and application thereof in olefin polymerization | 中国科学院化学研究所 | 2022-12-06 | — | — | CN | disclosed |
| CN-115433296-A | Catalyst composition and application thereof in olefin polymerization | 中国科学院化学研究所 | 2022-12-06 | — | — | CN | disclosed |
| US-5877265-A | Solid titanium catalyst component for olefin polymerization, process for preparing the same, catalyst for olefin polymerization and process for olefin polymerization | MITSUI CHEIMCALS, INC. (JP) | 1999-03-02 | — | — | US | disclosed |