Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | NCF1 | P14598 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ether SCHEMBL28930315 | 0.86 | LTA4H (0.34) | LTA4HTP53ALDH1A1KDM4ENCF1 | |
| SCHEMBL9765878 | 0.81 | LTA4H (0.31) | LTA4HTP53ALDH1A1NPC1RAB9A | |
| SCHEMBL523641 | 0.81 | LTA4H (0.31) | LTA4HTP53 | |
| Chloromethane SCHEMBL27870447 | 0.80 | ESR1 (0.39) | TP53ALDH1A1TSHRNPC1RAB9A | |
| Benzene SCHEMBL28183259 | 0.80 | TSHR (0.39) | ALDH1A1TSHRNPC1RAB9AESR1 | |
| SCHEMBL76000 | 0.80 | TSHR (0.39) | ALDH1A1TSHRNPC1RAB9AESR1 | |
| SCHEMBL29120692 | 0.80 | TSHR (0.39) | ALDH1A1TSHRNPC1RAB9AESR1 | |
| SCHEMBL705847 | 0.77 | ESR1 (0.40) | ALDH1A1TSHRNPC1RAB9AESR1 | |
| Fluoride SCHEMBL5604818 | 0.77 | TSHR (0.37) | ALDH1A1TSHRNPC1RAB9AESR1 | |
| Hydrochloric Acid SCHEMBL28179995 | 0.77 | TSHR (0.37) | ALDH1A1TSHRNPC1RAB9AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113603715-A | Preparation method of 10, 10-diphenylsilaacridine | 黑龙江省科学院石油化学研究院 | 2021-11-05 | — | — | CN | claimed |
| CN-113603715-A | Preparation method of 10, 10-diphenylsilaacridine | 黑龙江省科学院石油化学研究院 | 2021-11-05 | — | — | CN | disclosed |