Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 12/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 9/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 9/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 9/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GLA | P06280 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9603823 | 0.84 | DPP4 (0.44) | F2PRSS1PRSS2PRSS3DPP4 | |
| SCHEMBL14336163 | 0.83 | DPP4 (0.45) | F2PRSS1PRSS2PRSS3DPP4 | |
| SCHEMBL2226082 | 0.82 | DPP4 (0.46) | F2PRSS1PRSS2PRSS3DPP4 | |
| SCHEMBL12955580 | 0.81 | F2 (0.44) | F2PRSS1PRSS2PRSS3DPP4 | |
| SCHEMBL8469067 | 0.81 | CA12 (0.43) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL30522455 | 0.81 | CA12 (0.43) | F2PRSS1PRSS2PRSS3ALDH1A1 | |
| SCHEMBL28899291 | 0.81 | DPP4 (0.39) | F2PRSS1PRSS2PRSS3DPP4 | |
| SCHEMBL9396036 | 0.77 | DPP4 (0.43) | F2PRSS1PRSS2PRSS3DPP4 | |
| SCHEMBL5597236 | 0.75 | DPP4 (0.40) | F2PRSS1PRSS2PRSS3DPP4 | |
| SCHEMBL1498278 | 0.75 | F2 (0.42) | F2PRSS1PRSS2PRSS3DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5935802-A | Method of assaying a blood sample for prothrombin | EVANSTON NORTHWESTERN HEALTHCARE RESEARCH INSTITUTE (US) | 1999-08-10 | — | — | US | disclosed |