Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 20/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6297565 | 0.69 | CRHR1 (1.00) | CRHR1 | |
| SCHEMBL7533740 | 0.68 | CRHR1 (0.89) | CRHR1 | |
| SCHEMBL10670670 | 0.62 | SMN1; SMN2 (0.43) | CRHR1 | |
| SCHEMBL18000049 | 0.61 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL21851657 | 0.58 | TP53 (0.60) | CRHR1 | |
| SCHEMBL6297584 | 0.56 | CRHR1 (0.58) | CRHR1 | |
| SCHEMBL19121844 | 0.56 | ELANE (0.38) | CRHR1 | |
| SCHEMBL11217445 | 0.56 | CRHR1 (0.36) | CRHR1 | |
| SCHEMBL27555107 | 0.55 | S100B (0.36) | CRHR1 | |
| SCHEMBL9127003 | 0.55 | SMN1; SMN2 (0.42) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0923582-A1 | SUBSTITUTED 6,5-HETERO-BICYCLIC DERIVATIVES | PFIZER INC. (US) | 1999-06-23 | — | — | EP | disclosed |
| WO-1998008847-A1 | SUBSTITUTED 6,5-HETERO-BICYCLIC DERIVATIVES | PFIZER INC. (US) | 1998-03-05 | — | — | WO | disclosed |