Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8471691 | 0.88 | MAPT (0.59) | SNCAMAPTNPC1RAB9ACAPN9 | |
| SCHEMBL499539 | 0.83 | SNCA (0.49) | SNCAMAPTNPC1RAB9ACAPN9 | |
| SCHEMBL30970176 | 0.77 | TDP1 (0.50) | MAPTNPC1RAB9ACAPN9CASP3 | |
| SCHEMBL8968246 | 0.75 | SNCA (0.48) | SNCAMAPTNPC1RAB9ACAPN9 | |
| SCHEMBL499574 | 0.75 | MAOA (0.57) | SNCAMAPTNPC1RAB9ACAPN9 | |
| SCHEMBL29625234 | 0.74 | SNCA (0.84) | SNCAMAPTNPC1RAB9ACAPN9 | |
| SCHEMBL1208092 | 0.74 | SNCA (0.84) | SNCAMAPTNPC1RAB9ACAPN9 | |
| SCHEMBL8115442 | 0.73 | SNCA (0.54) | SNCAMAPTNPC1RAB9ACAPN9 | |
| SCHEMBL10353386 | 0.72 | SNCA (0.52) | SNCAMAPTNPC1RAB9ACAPN9 | |
| SCHEMBL24982 | 0.72 | MAPT (0.49) | SNCAMAPTNPC1RAB9ACAPN9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204018-B | Acrylic compound, preparation method, pharmaceutical composition and application thereof | 中国科学院上海药物研究所 | 2023-08-29 | — | — | CN | disclosed |
| CN-111170961-B | Photocatalytic synthesis method of C2 substituted 2H-benzothiazole hydroxyalkylation derivative | 浙江工业大学 | 2021-11-02 | — | — | CN | disclosed |
| CN-111170961-A | Photocatalytic synthesis method of C2 substituted 2H-benzothiazole hydroxyalkylation derivative | 浙江工业大学 | 2020-05-19 | — | — | CN | disclosed |
| US-5968725-A | MATERIAL COMPRISING ON SUPPORT SILVER HALIDE PHOTOSENSITIVE LAYER CONTAINING ORGANIC SILVER SALT, REDUCING AGENT, ULTRAHIGH CONTRAST PROMOTING AGENT, SELECTED HETEROCYCLIC MERCAPTO COMPOUND | FUJI PHOTO FILM CO., LTD. (JP) | 1999-10-19 | — | — | US | disclosed |
| US-5236807-A | Negative, hydrazine compound | FUJI PHOTO FILM CO., LTD. (JP) | 1993-08-17 | — | — | US | disclosed |
| US-4769316-A | Method for restraining the formation of re-reversal negative image in direct positive silver halide photographic materials | FUJI PHOTO FILM CO., LTD. (JP) | 1988-09-06 | — | — | US | disclosed |