Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.41 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.40 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6591835 | 0.79 | PNMT (0.44) | SNCAMAPTNPC1RAB9ACA12 | |
| SCHEMBL8469291 | 0.75 | SNCA (0.51) | SNCAMAPTNPC1RAB9ANOX1 | |
| SCHEMBL8968538 | 0.73 | KDM4E (0.39) | MAPTCA12CA9ABCC8KCNJ11 | |
| SCHEMBL499539 | 0.72 | SNCA (0.49) | SNCAMAPTNPC1RAB9ANOX1 | |
| SCHEMBL8968231 | 0.72 | CAPN9 (0.49) | MAPTRAB9ACA12CA9CAPN9 | |
| Hydrochloric Acid SCHEMBL8968458 | 0.71 | KDM4E (0.38) | MAPTCA12CA9ABCC8KCNJ11 | |
| SCHEMBL499574 | 0.71 | MAOA (0.57) | SNCAMAPTNPC1RAB9ANOX1 | |
| SCHEMBL1208092 | 0.70 | SNCA (0.84) | SNCAMAPTNPC1RAB9ANOX1 | |
| SCHEMBL29625234 | 0.70 | SNCA (0.84) | SNCAMAPTNPC1RAB9ANOX1 | |
| SCHEMBL8968000 | 0.70 | CA12 (0.47) | SNCAMAPTNPC1RAB9ACA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5504095-A | Aminobenzosultam derivatives as lipoxygenase inhibitors | PFIZER INC. (US) | 1996-04-02 | — | — | US | disclosed |
| EP-0549666-B1 | NOVEL AMINOBENZOSULTAM DERIVATIVES AS LIPOXYGENASE INHIBITORS | PFIZER (US) | 1994-11-23 | — | — | EP | disclosed |
| EP-0549666-A1 | NOVEL AMINOBENZOSULTAM DERIVATIVES AS LIPOXYGENASE INHIBITORS. | PFIZER (US) | 1993-07-07 | — | — | EP | disclosed |
| WO-1992005164-A1 | NOVEL AMINOBENZOSULTAM DERIVATIVES AS LIPOXYGENASE INHIBITORS | PFIZER INC. (US) | 1992-04-02 | — | — | WO | disclosed |