Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SNCA | P37840 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.46 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | CAPN9 | O14815 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.41 |
| ▸ | CDK1 | P06493 | 1/20 | 0.41 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL499574 | 0.83 | MAOA (0.57) | SNCANOX1NPC1MAPTRAB9A | |
| SCHEMBL29625234 | 0.76 | SNCA (0.84) | SNCANOX1NPC1MAPTRAB9A | |
| SCHEMBL1208092 | 0.76 | SNCA (0.84) | SNCANOX1NPC1MAPTRAB9A | |
| SCHEMBL10353386 | 0.74 | SNCA (0.52) | SNCANOX1NPC1MAPTRAB9A | |
| SCHEMBL8469291 | 0.73 | SNCA (0.51) | SNCAALDH1A1NOX1NPC1MAPT | |
| SCHEMBL2125595 | 0.72 | HTT (0.54) | SNCAALDH1A1NOX1NPC1MAPT | |
| SCHEMBL7450900 | 0.71 | ALDH1A1 (0.59) | ALDH1A1NOX1MAPTCDK1MEN1 | |
| SCHEMBL7449747 | 0.71 | ALDH1A1 (0.59) | ALDH1A1CHRM1NOX1MAPT | |
| SCHEMBL29214094 | 0.71 | SNCA (0.79) | SNCANOX1NPC1MAPTRAB9A | |
| SCHEMBL30867073 | 0.71 | SNCA (0.79) | SNCANOX1NPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1054889-A1 | NEW OXAZOLIDINONES WITH AZOL-CONTAINING TRICYCLES | Bayer Aktiengesellschaft (DE) | 2000-11-29 | — | — | EP | disclosed |
| WO-1999040094-A1 | AGENT FOR SEALING METALLIC GROUND COATS, ESPECIALLY GROUND COATS CONSISTING OF ZINC OR ZINC ALLOYS | BAYER AKTIENGESELLSCHAFT (DE) | 1999-08-12 | — | — | WO | disclosed |