Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARA | P10276 | 2/20 | 0.42 |
| ▸ | RARB | P10826 | 2/20 | 0.42 |
| ▸ | RARG | P13631 | 2/20 | 0.42 |
| ▸ | SYK | P43405 | 2/20 | 0.35 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8331032 | 0.90 | RARA (0.53) | RARARARBRARGSYKRXFP1 | |
| SCHEMBL8329461 | 0.83 | RARA (0.49) | RARARARBRARGSYKPTPN11 | |
| SCHEMBL8327517 | 0.83 | RARA (0.40) | RARARARBRARGSYKPTPN11 | |
| SCHEMBL8331248 | 0.70 | RARB (0.38) | RARARARBRARGNPSR1 | |
| SCHEMBL8469318 | 0.69 | RARA (0.37) | RARARARBRARG | |
| SCHEMBL8331925 | 0.65 | RARA (0.48) | RARARARBRARGNPSR1RXFP1 | |
| SCHEMBL8333153 | 0.65 | RARA (0.48) | RARARARBRARG | |
| SCHEMBL7179753 | 0.64 | SLC6A2 (0.54) | SYKPTPN11 | |
| SCHEMBL10984209 | 0.64 | HNF4A (0.58) | SYK | |
| SCHEMBL8329653 | 0.64 | RARA (0.37) | RARARARBRARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5958954-A | 2,2-DIALKYL-4-ARYL-SUBSTITUTED BENZOPYRAN AND BENZOTHIOPYRAN DERIVATIVES | ALLERGAN SALES, INC. (US) | 1999-09-28 | — | — | US | disclosed |