Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.41 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469225 | 0.91 | ALDH1A1 (0.48) | LMNAKDM4EKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL8471286 | 0.91 | LMNA (0.45) | LMNAKDM4EKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL9407911 | 0.88 | LMNA (0.49) | LMNAKDM4EKEAP1NFE2L2SMN1; SMN2 | |
| Bromide SCHEMBL8469899 | 0.87 | KEAP1 (0.45) | LMNAKEAP1NFE2L2ALDH1A1MAPT | |
| SCHEMBL8469584 | 0.86 | MAPT (0.53) | LMNAKDM4EKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL8471272 | 0.85 | ALDH1A1 (0.46) | LMNAKEAP1NFE2L2ALDH1A1GAA | |
| SCHEMBL8470011 | 0.84 | ALDH1A1 (0.44) | LMNAKDM4EKEAP1NFE2L2SMN1; SMN2 | |
| SCHEMBL8469910 | 0.84 | LMNA (0.38) | LMNAKDM4EKEAP1NFE2L2ALDH1A1 | |
| SCHEMBL8136893 | 0.81 | TP53 (0.49) | LMNAKDM4EKEAP1NFE2L2ALDH1A1 | |
| Bromide SCHEMBL8471291 | 0.81 | KEAP1 (0.46) | LMNAKDM4EKEAP1NFE2L2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6002007-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 1999-12-14 | — | — | US | disclosed |
| US-5879953-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5783696-A | Special chemiluminescent acridine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |