Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 11/20 | 0.61 |
| ▸ | HSD17B2 | P37059 | 10/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.61 |
| ▸ | RXRA | P19793 | 1/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.55 |
| ▸ | ESR1 | P03372 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.52 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.49 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2095173 | 0.83 | HSD17B1 (0.49) | HSD17B1HSD17B2CYP2C9CYP3A4RXRA | |
| SCHEMBL8189613 | 0.82 | HSD17B1 (0.61) | HSD17B1HSD17B2CYP2C9CYP3A4ESR1 | |
| SCHEMBL8524895 | 0.82 | RXRA (0.69) | HSD17B1HSD17B2CYP2C9CYP3A4RXRA | |
| SCHEMBL863444 | 0.81 | ESR2 (0.58) | CYP2C9ESR1CYP1A2CYP2C19ESR2 | |
| SCHEMBL1026075 | 0.79 | HSD17B1 (0.68) | HSD17B1HSD17B2CYP2C9CYP3A4ESR1 | |
| SCHEMBL6002565 | 0.79 | HSD17B1 (0.53) | HSD17B1HSD17B2CYP2C9CYP3A4ESR1 | |
| SCHEMBL30398332 | 0.79 | CYP3A4 (0.62) | HSD17B1HSD17B2CYP3A4RXRARXRB | |
| SCHEMBL105731 | 0.79 | CYP3A4 (0.62) | HSD17B1HSD17B2CYP3A4RXRARXRB | |
| SCHEMBL4677364 | 0.79 | HSD17B1 (0.74) | HSD17B1HSD17B2CYP2C9CYP3A4ESR1 | |
| SCHEMBL2096774 | 0.79 | RXRA (0.51) | CYP2C9RXRARXRBCYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999025707-A1 | 2-ARYLBENZO[b]THIOPHENES USEFUL FOR THE TREATMENT OF ESTROGEN DEPRIVATION SYNDROME | ELI LILLY AND COMPANY (US) | 1999-05-27 | — | — | WO | claimed |