Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 6/20 | 0.37 |
| ▸ | SIGMAR1 known ✓ | Q99720 | 1/20 | 0.33 |
| ▸ | INMT | O95050 | 4/20 | 0.95 |
| ▸ | USP2 | O75604 | 2/20 | 0.95 |
| ▸ | NOS3 | P29474 | 3/20 | 0.34 |
| ▸ | NOS1 | P29475 | 3/20 | 0.34 |
| ▸ | NOS2 | P35228 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL14761484 | 1.00 | INMT (0.95) | INMTUSP2ACHENOS3NOS1 | |
| Bromide SCHEMBL29980319 | 0.98 | INMT (0.91) | INMTUSP2ACHENOS3NOS1 | |
| SCHEMBL3047 | 0.98 | INMT (1.00) | INMTUSP2ACHENOS3NOS1 | |
| SCHEMBL10601682 | 0.98 | INMT (1.00) | INMTUSP2ACHENOS3NOS1 | |
| SCHEMBL17417853 | 0.98 | INMT (1.00) | INMTUSP2ACHENOS3NOS1 | |
| SCHEMBL16583523 | 0.98 | INMT (1.00) | INMTUSP2ACHENOS3NOS1 | |
| SCHEMBL2734323 | 0.98 | INMT (1.00) | INMTUSP2ACHENOS3NOS1 | |
| Bromide SCHEMBL18093523 | 0.96 | INMT (0.88) | INMTUSP2ACHENOS3NOS1 | |
| Bromide SCHEMBL29732962 | 0.96 | INMT (0.88) | INMTUSP2ACHENOS3NOS1 | |
| Iodide SCHEMBL23365018 | 0.95 | INMT (0.95) | INMTUSP2ACHENOS3NOS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022212727-A1 | METHOD OF CONVERSION OF LACTIC ACID AND POLYLACTIC ACID TO ACRYLIC ACID OR ACRYLATES IN LIQUID PHASE | NITTO DENKO CORPORATION (JP) | 2022-10-06 | — | — | WO | claimed |
| EP-3583088-B1 | SYNTHESIS OF PHEROMONES AND RELATED MATERIALS VIA OLEFIN METATHESIS | PROVIVI INC (US) | 2025-09-10 | — | — | EP | disclosed |
| CN-110603240-B | Synthesis of pheromones and related substances via olefin metathesis | 普罗维维公司 | 2022-11-15 | — | — | CN | disclosed |
| CN-114478510-B | Preparation method of nifuratel | 盐城凯利药业有限公司 | 2022-11-01 | — | — | CN | disclosed |
| WO-2022212727-A1 | METHOD OF CONVERSION OF LACTIC ACID AND POLYLACTIC ACID TO ACRYLIC ACID OR ACRYLATES IN LIQUID PHASE | NITTO DENKO CORPORATION (JP) | 2022-10-06 | — | — | WO | disclosed |
| CN-114478510-A | Preparation method of nifuratel | 盐城凯利药业有限公司 | 2022-05-13 | — | — | CN | disclosed |
| US-11155505-B2 | Synthesis of pheromones and related materials via olefin metathesis | PROVIVI, INC. (US) | 2021-10-26 | — | — | US | disclosed |
| US-20200039900-A1 | SYNTHESIS OF PHEROMONES AND RELATED MATERIALS VIA OLEFIN METATHESIS | PROVIVI, INC. (US) | 2020-02-06 | — | — | US | disclosed |
| WO-1999028355-A1 | FUNCTIONAL POLYMERS WITH CARBON-LINKED FUNCTIONAL GROUPS | ACTIVE MATERIALS INC. (CA) | 1999-06-10 | — | — | WO | disclosed |
| EP-0634456-B1 | VULCANIZABLE FLUOROELASTOMER COMPOSITION | DU PONT (US) | 1998-11-18 | — | — | EP | disclosed |
| US-5508355-A | CONTAINING A POLYOL VULCANIZER, ALIPHATIC AMINE AND CATIONIC ACCELERATOR; IMPROVED MOLD RELEASE, WORKABILITY IN INJECTIONMOLDING | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-04-16 | — | — | US | disclosed |
| EP-0634456-A1 | VULCANIZABLE FLUOROELASTOMER COMPOSITION | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1995-01-18 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039900-A1 | SYNTHESIS OF PHEROMONES AND RELATED MATERIALS VIA OLEFIN METATHESIS | OSBPL8, CYP51A1, ERG28 | ACHE 748/4885SIGMAR1 1685/4885INMT 2427/4885 |
| US-11155505-B2 | Synthesis of pheromones and related materials via olefin metathesis | OSBPL8, CYP51A1, ERG28 | ACHE 748/4885SIGMAR1 1685/4885INMT 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.