Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | HTR7 | P34969 | 1/20 | 0.50 |
| ▸ | HTR2B | P41595 | 1/20 | 0.50 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GPR3 | P46089 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL4820941 | 0.91 | HTR7 (0.50) | POLBHTR7HTR2BHDAC3HDAC4 | |
| SCHEMBL29641604 | 0.87 | GPR3 (0.52) | POLBHTR7HTR2BHDAC3HDAC4 | |
| SCHEMBL40599 | 0.87 | GPR3 (0.52) | POLBHTR7HTR2BHDAC3HDAC4 | |
| SCHEMBL10965346 | 0.81 | HTR7 (0.62) | POLBHTR7HTR2BKMT2AMEN1 | |
| SCHEMBL6901219 | 0.78 | CDC25B (0.52) | POLBHTR7HTR2BNCOR2KMT2A | |
| SCHEMBL30045412 | 0.78 | HTR7 (0.40) | POLBHTR7HTR2BHDAC3HDAC4 | |
| SCHEMBL26119869 | 0.77 | TTR (0.51) | POLBHTR7HTR2BKMT2AMEN1 | |
| SCHEMBL30571871 | 0.77 | HTR7 (0.62) | POLBHTR7HTR2BKMT2AMEN1 | |
| SCHEMBL7825562 | 0.77 | HTR7 (0.62) | POLBHTR7HTR2BKMT2AMEN1 | |
| SCHEMBL7043488 | 0.76 | HDAC3 (0.57) | POLBHDAC3HDAC4HDAC7HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0848693-A4 | ISOMERIZATION OF BISPHENOLS | DOW CHEMICAL CO (US) | 1999-03-17 | — | — | EP | disclosed |
| EP-0848693-A1 | ISOMERIZATION OF BISPHENOLS | THE DOW CHEMICAL COMPANY (US) | 1998-06-24 | — | — | EP | disclosed |
| WO-1997008122-A1 | ISOMERIZATION OF BISPHENOLS | THE DOW CHEMICAL COMPANY (US) | 1997-03-06 | — | — | WO | disclosed |