Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13603966 | 0.85 | ALDH1A1 (0.46) | LMNAALDH1A1TSHRGLATP53 | |
| SCHEMBL20293769 | 0.84 | TP53 (0.57) | LMNAALDH1A1TSHRGLATP53 | |
| SCHEMBL10442749 | 0.84 | LMNA (0.43) | LMNAALDH1A1TSHRGLATP53 | |
| SCHEMBL14588682 | 0.79 | ALDH1A1 (0.52) | LMNAALDH1A1KMT2ACRHBPCRHR2 | |
| SCHEMBL6002982 | 0.77 | TSHR (0.46) | LMNAALDH1A1TSHRGLATP53 | |
| SCHEMBL10442704 | 0.77 | HPGD (0.40) | LMNAALDH1A1TSHRGLATP53 | |
| SCHEMBL6001172 | 0.76 | TSHR (0.47) | LMNAALDH1A1TSHRGLATP53 | |
| SCHEMBL6002978 | 0.76 | TSHR (0.45) | LMNAALDH1A1TSHRGLATP53 | |
| SCHEMBL9505872 | 0.75 | KMT2A (0.46) | ALDH1A1TSHRGLAMTNR1AMTNR1B | |
| SCHEMBL8395346 | 0.75 | CYP3A4 (0.44) | LMNAALDH1A1TSHRGLATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1376146-B | Solid-state form of celecoxil having enhanced bioavailability | PHARMACIA CORP | 2011-04-06 | — | — | CN | disclosed |
| WO-1999031030-A1 | O-ALKYLATION OF PHENOL COMPOUNDS | RHODIA-CHIMIE (FR) | 1999-06-24 | — | — | WO | disclosed |
| CN-1049846-A | Glutarimide with weeding activity | ROHM & HAAS (US) | 1991-03-13 | — | — | CN | disclosed |