SCHEMBL8470261

SCHEMBL8470261

Fc1ccc(F)c(-c2c(F)c(F)c(F)c(F)c2F)c1F

nearest known ligand 0.35

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.35
CES1 P23141 1/20 0.35
PTGS2 P35354 9/20 0.33
PTGS1 P23219 4/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18274985 0.75 CES2 (0.39) CES2CES1
SCHEMBL17779399 0.75 PTGS2 (0.39) PTGS2PTGS1
SCHEMBL1685614 0.75 LMNA (0.42) PTGS2PTGS1
SCHEMBL185143 0.73 CA1 (0.38) CES2CES1
SCHEMBL31711774 0.73 CES2 (0.34) CES2CES1PTGS2PTGS1
SCHEMBL20921666 0.71 PTGS2 (0.36) PTGS2PTGS1
SCHEMBL45430 0.71 CES2 (0.53) CES2CES1
SCHEMBL12693559 0.71 CA1 (0.31)
SCHEMBL12352227 0.71 CA1 (0.36) CES2CES1
SCHEMBL31711754 0.71 CA1 (0.36) CES2CES1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016079144-A1 FLUORINATED AROMATIC SMALL MOLECULES AS FUNCTIONAL ADDITIVES FOR DISPERSION OF CONDUCTIVE POLYMERS Heraeus Deutschland GmbH & Co. KG (DE) 2016-05-26 WO disclosed
EP-3024049-A1 Fluorinated aromatic small molecules as functional additives for dispersion of conductive polymers Heraeus Deutschland GmbH & Co. KG (DE) 2016-05-25 EP disclosed
EP-0954540-A1 A PROCESS FOR POLYMERIZING OLEFINS DSM N.V. (NL) 1999-11-10 EP disclosed
WO-1998030603-A1 A PROCESS FOR POLYMERIZING OLEFINS DSM N.V. (NL) 1998-07-16 WO disclosed