SCHEMBL185143

SCHEMBL185143

Fc1cc(F)c(F)c(-c2c(F)c(F)c(F)c(F)c2F)c1F

nearest known ligand 0.38

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
CA1 P00915 3/20 0.38
CA2 P00918 3/20 0.38
CA4 P22748 2/20 0.38
CA12 O43570 1/20 0.38
CA7 P43166 1/20 0.38
CA13 Q8N1Q1 1/20 0.38
CES2 O00748 2/20 0.35
CES1 P23141 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31711755 0.97 CA1 (0.36) CA1CA2CA4CA12CA7
SCHEMBL31711754 0.97 CA1 (0.36) CA1CA2CA4CA12CA7
SCHEMBL12352227 0.97 CA1 (0.36) CA1CA2CA4CA12CA7
SCHEMBL31711743 0.97 CA1 (0.36) CA1CA2CA4CA12CA7
SCHEMBL31711742 0.96 CA1 (0.39) CA1CA2CA4CA12CA7
SCHEMBL1995798 0.93 CA1 (0.41) CA1CA2CA4CA12CA7
Ammonia Solution, Strong SCHEMBL6003881 0.89 CA1 (0.39) CA1CA2CA4CA12CA7
SCHEMBL5086821 0.89 CA1 (0.39) CA1CA2CA4CA12CA7
SCHEMBL21201794 0.88 NPC1 (0.33) CA1CA2CA4CA12CA7
SCHEMBL2937298 0.88 NPC1 (0.38) CA1CA2CA4CA12CA7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 133 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240018279-A1 Cyclic Containing Polymer Compositions Obtained Using Transition Metal Bis(Phenolate) Catalyst Complexes and Process for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2024-01-18 US disclosed
US-20230348634-A1 Propylene Polymers Obtained Using Transition Metal Bis(Phenolate) Catalyst Complexes and Homogeneous Process for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-02 US disclosed
US-20230348640-A1 Propylene Copolymers Obtained Using Transition Metal Bis(Phenolate) Catalyst Complexes and Homogeneous Process for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-02 US disclosed
US-20230348642-A1 Ethylene-Alpha-Olefin-Diene Monomer Copolymers Obtained Using Transition Metal Bis(Phenolate) Catalyst Complexes and Homogeneous Process for Production Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-11-02 US disclosed
US-20230312772-A1 Multidentate Lewis Base Catalysts and Methods for use Thereof EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-10-05 US disclosed
US-11766669-B2 Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-09-26 US disclosed
US-11738334-B2 Supported catalyst systems and processes for use thereof EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-29 US disclosed
US-11739169-B2 Solubility improvement of non-metallocene transition metal complexes in aliphatic hydrocarbon solvents EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-08-29 US disclosed
US-20230212330-A1 Metallocene Catalysts for Producing Vinyl-Terminated Polyalphaolefins and Methods Associated Therewith EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-07-06 US disclosed
US-11661465-B2 Dimer selective metallocene catalysts, non-aromatic hydrocarbon soluble activators, and processes to produce poly alpha-olefin oligmers therewith EXXONMOBIL CHEMICAL PATENTS INC. (US) 2023-05-30 US disclosed
WO-2011000939-A1 USE OF SUBSTITUTED PERIFLANTHENES IN ORGANIC SOLAR CELLS BASF SE (DE) 2011-01-06 WO disclosed
WO-2010097433-A1 QUINONE COMPOUNDS AS DOPANTS IN ORGANIC ELECTRONICS BASF SE (DE) 2010-09-02 WO disclosed
EP-2181172-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF BASF SE (DE) 2010-05-05 EP disclosed
WO-2009147237-A1 CHLORINATED NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2009-12-10 WO disclosed
US-20090301552-A1 CHLORINATED NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN ORGANIC ELECTRONICS BASF SE (DE) 2009-12-10 US disclosed
US-20090166614-A1 FLUORINATED RYLENETETRACARBOXYLIC ACID DERIVATIVES AND USE THEREOF BASF AKTIENGESELLSCHAFT (DE) 2009-07-02 US disclosed
WO-2009024512-A1 HALOGEN-CONTAINING PERYLENETETRACARBOXYLIC ACID DERIVATIVES AND THE USE THEREOF BASF SE (DE) 2009-02-26 WO disclosed
WO-2009000831-A1 BROMINE-SUBSTITUTED RYLENE TETRACARBOXYLIC ACID DERIVATIVES, AND THE USE THEREOF BASF SE (DE) 2008-12-31 WO disclosed
US-6129863-A Clean generation of a perfluoroaryl grignard reagent ALBEMARLE CORPORATION (US) 2000-10-10 US disclosed
WO-2000035923-A1 CLEAN GENERATION OF A PERFLUOROARYL GRIGNARD REAGENT ALBEMARLE CORPORATION (US) 2000-06-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090301552-A1 CHLORINATED NAPHTHALENETETRACARBOXYLIC ACID DERIVATIVES, PREPARATION THEREOF AND USE THEREOF IN ORGANIC ELECTRONICS SLCO2A1, SLCO4C1, SLCO2B1 CA1 520/4885CA2 328/4885CA4 343/4885
US-11766669-B2 Hexahydrocyclopenta[e]-as-indacen-1-yl and octahydrobenzo[e]-as-indacen-1-yl based catalyst complexes and process for use thereof MLX, ZYX, TXN CA1 4054/4885CA2 3255/4885CA4 4465/4885
US-20090166614-A1 FLUORINATED RYLENETETRACARBOXYLIC ACID DERIVATIVES AND USE THEREOF FXR2, FXR1, FTO CA1 143/4885CA2 1294/4885CA4 347/4885
US-11661465-B2 Dimer selective metallocene catalysts, non-aromatic hydrocarbon soluble activators, and processes to produce poly alpha-olefin oligmers therewith NONO, TPR, ZNF787 CA1 2086/4885CA2 3246/4885CA4 2616/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.