Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.33 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472099 | 0.97 | TP53 (0.35) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL31163692 | 0.93 | LMNA (0.40) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL8469774 | 0.89 | LMNA (0.39) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL8469537 | 0.89 | ALDH1A1 (0.39) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL8469910 | 0.89 | LMNA (0.38) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| Trifluoromethanesulfonic Acid SCHEMBL4426555 | 0.87 | ALDH1A1 (0.37) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL8469304 | 0.85 | TSHR (0.39) | TP53LMNAMAPTGAAALDH1A1 | |
| SCHEMBL8469668 | 0.84 | ALDH1A1 (0.37) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL8470361 | 0.83 | LMNA (0.41) | TP53LMNAMAPTCYP1A2CYP3A4 | |
| SCHEMBL13433231 | 0.81 | ALDH1A1 (0.38) | TP53LMNAMAPTCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6002007-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 1999-12-14 | — | — | US | disclosed |