Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | F2 | P00734 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.36 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469537 | 0.95 | ALDH1A1 (0.39) | ALDH1A1KMT2AF2HPGDPOLB | |
| Trifluoromethanesulfonic Acid SCHEMBL4426555 | 0.90 | ALDH1A1 (0.37) | ALDH1A1KMT2AF2HPGDPOLB | |
| SCHEMBL8472099 | 0.88 | TP53 (0.35) | ALDH1A1TP53MAPTGAAKEAP1 | |
| SCHEMBL8470438 | 0.87 | ALDH1A1 (0.42) | ALDH1A1KMT2AF2HPGDPOLB | |
| SCHEMBL8469157 | 0.84 | KEAP1 (0.36) | ALDH1A1KMT2AHPGDMAPTGAA | |
| SCHEMBL8470372 | 0.84 | TP53 (0.37) | ALDH1A1TP53MAPTGAAKEAP1 | |
| SCHEMBL8469774 | 0.83 | LMNA (0.39) | TP53MAPTGAAKEAP1NFE2L2 | |
| SCHEMBL8469304 | 0.82 | TSHR (0.39) | ALDH1A1KMT2AHPGDPOLBTP53 | |
| SCHEMBL8470105 | 0.81 | ALDH1A1 (0.43) | ALDH1A1KMT2AF2HPGDPOLB | |
| SCHEMBL13433231 | 0.81 | ALDH1A1 (0.38) | ALDH1A1KMT2AF2HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6002007-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 1999-12-14 | — | — | US | claimed |
| US-6002007-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | DADE BEHRING MARBURG GMBH (DE) | 1999-12-14 | — | — | US | disclosed |
| US-5879953-A | Special chemiluminescent acridine derivatives and the use thereof in luminescence immunoassays | HOECHST AKTIENGESELLSCHAFT (DE) | 1999-03-09 | — | — | US | disclosed |
| US-5783696-A | Special chemiluminescent acridine derivatives | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-21 | — | — | US | disclosed |