Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | F2 | P00734 | 3/20 | 0.38 |
| ▸ | TP53 | P04637 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8469537 | 0.86 | ALDH1A1 (0.39) | ALDH1A1KMT2AHPGDF2TP53 | |
| Trifluoromethanesulfonic Acid SCHEMBL4426555 | 0.84 | ALDH1A1 (0.37) | ALDH1A1KMT2AHPGDF2TP53 | |
| SCHEMBL8469668 | 0.81 | ALDH1A1 (0.37) | ALDH1A1KMT2AHPGDF2TP53 | |
| SCHEMBL8470372 | 0.81 | TP53 (0.37) | ALDH1A1TP53LMNAKEAP1HSP90AA1 | |
| SCHEMBL8472099 | 0.79 | TP53 (0.35) | ALDH1A1TP53LMNAKEAP1HSP90AA1 | |
| SCHEMBL8470105 | 0.79 | ALDH1A1 (0.43) | ALDH1A1KMT2AHPGDF2TP53 | |
| SCHEMBL8469157 | 0.76 | KEAP1 (0.36) | ALDH1A1KMT2AHPGDLMNAKEAP1 | |
| SCHEMBL8469304 | 0.75 | TSHR (0.39) | ALDH1A1KMT2AHPGDTP53LMNA | |
| SCHEMBL31163692 | 0.74 | LMNA (0.40) | TP53LMNAKEAP1HSP90AA1MAPT | |
| SCHEMBL8470438 | 0.74 | ALDH1A1 (0.42) | ALDH1A1KMT2AHPGDF2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7695980-B2 | Chemiluminescent compounds and their use | ROCHE DIAGNOSTICS OPERATIONS, INC. (US) | 2010-04-13 | — | — | US | disclosed |