Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 4/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | THPO | P40225 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1953246 | 0.79 | PNMT (0.44) | DRD1DRD2 | |
| SCHEMBL3957205 | 0.78 | ADRA1D (0.62) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| Bromide SCHEMBL6521671 | 0.77 | ADRA1D (0.61) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL1951737 | 0.76 | HDAC3 (0.39) | KDM4EDRD2 | |
| SCHEMBL4513446 | 0.75 | DRD2 (0.42) | DRD1CYP2D6MAPTDRD2LMNA | |
| SCHEMBL697563 | 0.74 | SIGMAR1 (0.50) | ADRA1DADRA1AADRA1BADRA2AADRA2B | |
| SCHEMBL1953017 | 0.73 | MEN1 (0.43) | KDM4ECYP2D6MAPTTDP1DRD2 | |
| SCHEMBL1953429 | 0.73 | CARM1 (0.45) | LMNA | |
| SCHEMBL951185 | 0.73 | MEN1 (0.40) | KDM4EMAPTDRD2 | |
| SCHEMBL1204903 | 0.73 | KMT2A (0.35) | CYP2D6MAPTLMNASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5919795-A | ATHEROSCLEROSIS THERAPY | PFIZER INC. (US) | 1999-07-06 | — | — | US | claimed |