SCHEMBL847110

SCHEMBL847110

O=C1CCC2(CCO1)OCCO2

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.43
ALDH1A1 P00352 1/20 0.43
TP53 P04637 1/20 0.43
TSHR P16473 1/20 0.43
CA1 P00915 1/20 0.41
CA9 Q16790 1/20 0.41
CYP2C9 P11712 1/20 0.38
GAA P10253 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30
POLB P06746 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10063742 0.79 LMNA (0.48) LMNAALDH1A1TP53TSHRCA1
SCHEMBL46361 0.75 KMT2A (0.34) LMNAALDH1A1TP53TSHRCYP2C9
Water SCHEMBL31387323 0.73 ALDH1A1 (0.33) LMNAALDH1A1TP53TSHRCYP2C9
SCHEMBL4134507 0.70 LMNA (0.48) LMNAALDH1A1TP53TSHRCA1
SCHEMBL31163780 0.70 LMNA (0.46) LMNAALDH1A1TP53TSHRCA1
SCHEMBL5528579 0.70 CRBN (0.40) LMNAALDH1A1CYP2C9GAAL3MBTL1
SCHEMBL13276962 0.68 TRIM24 (0.39) LMNAALDH1A1CYP2C9GAAL3MBTL1
SCHEMBL31715737 0.68 GAA (0.33) ALDH1A1CYP2C9GAAL3MBTL1POLB
SCHEMBL2650564 0.67 POLB (0.31) LMNATP53L3MBTL1POLBKDM4E
SCHEMBL6594728 0.67 POLB (0.31) LMNATP53L3MBTL1POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116854899-A Flexible high polymer material with self-repairing performance and preparation method thereof 暨南大学 2023-10-10 CN claimed
CN-116790126-A Flexible high polymer material with glucose response, preparation method thereof and application thereof in preparation of biosensor 暨南大学 2023-09-22 CN claimed
CN-113057909-B Intelligent thermotropic hydrogel skin care film and preparation method and application thereof 复旦大学 2022-10-18 CN claimed
CN-111548482-B Nitric oxide donor modified copolymer, sustained-release preparation containing nitric oxide donor modified copolymer, and preparation method and application of nitric oxide donor modified copolymer 复旦大学 2022-09-13 CN claimed
CN-112250888-B X-ray development thermotropic hydrogel and preparation method and application thereof 复旦大学 2022-04-01 CN claimed
CN-112043827-B Thermo-sensitive pharmaceutical composition, transdermal preparation, and preparation method and application thereof 复旦大学 2023-10-20 CN disclosed
CN-116854899-A Flexible high polymer material with self-repairing performance and preparation method thereof 暨南大学 2023-10-10 CN disclosed
CN-116854899-A Flexible high polymer material with self-repairing performance and preparation method thereof 暨南大学 2023-10-10 CN disclosed
CN-116790126-A Flexible high polymer material with glucose response, preparation method thereof and application thereof in preparation of biosensor 暨南大学 2023-09-22 CN disclosed
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2023-07-04 US disclosed
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers CORAL BAY II, LLC (US) 2023-07-04 US disclosed
CN-113057909-B Intelligent thermotropic hydrogel skin care film and preparation method and application thereof 复旦大学 2022-10-18 CN disclosed
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed
US-20100305300-A1 Method of Ring-Opening Polymerization, and Related Compositions and Articles INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed
US-20100305300-A1 Method of Ring-Opening Polymerization, and Related Compositions and Articles INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2010-12-02 US disclosed
CN-101864065-A Biodegradable amphiphilic block copolymer containing cyclic ether side group and preparation method and applications thereof UNIV TIANJIN 2010-10-20 CN disclosed
US-6348564-B1 UNSUBSTITUTED OXEPANE-DIONES PREPARED BY OXIDATION OF CYCLOHEXANEDIONES; BIOCOMPATIBILITY, BIODEGRADATION, NONTOXIC SOLVAY (SOCIETE ANONYME) (BE) 2002-02-19 US disclosed
EP-1061079-A1 Cyclic esterketone compounds and processes for the synthesis and use thereof SOLVAY (Société Anonyme) (BE) 2000-12-20 EP disclosed
EP-1061078-A1 Cyclic esterketone compounds, processes for the synthesis thereof and process for the preparation of poly(esterketone)polymers SOLVAY (Société Anonyme) (BE) 2000-12-20 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11690380-B2 Antimicrobial guanidinium and thiouronium functionalized polymers PUF60, CAPG, GMPS LMNA 4337/4885ALDH1A1 4488/4885TP53 1207/4885
US-20100305281-A1 POLYMERS BEARING PENDANT PENTAFLUOROPHENYL ESTER GROUPS, AND METHODS OF SYNTHESIS AND FUNCTIONALIZATION THEREOF PFAS, PAM, PCNA LMNA 1875/4885ALDH1A1 618/4885TP53 4006/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.