Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.54 |
| ▸ | HTR6 | P50406 | 2/20 | 0.53 |
| ▸ | HTR1A | P08908 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
| ▸ | DRD4 | P21917 | 1/20 | 0.53 |
| ▸ | HTR1D | P28221 | 1/20 | 0.53 |
| ▸ | HTR1B | P28222 | 1/20 | 0.53 |
| ▸ | HTR1F | P30939 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.51 |
| ▸ | TUBB | P07437 | 3/20 | 0.51 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.51 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.51 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.51 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.51 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.51 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.51 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475171 | 0.90 | KDM4E (0.56) | KDM4EHTR6HTR1ADRD2DRD4 | |
| SCHEMBL8472591 | 0.90 | MEN1 (0.62) | KDM4EHTR6HTR1ADRD2DRD4 | |
| SCHEMBL8472332 | 0.88 | KDM4E (0.54) | KDM4EHTR6HTR1ADRD2DRD4 | |
| SCHEMBL19661278 | 0.88 | MEN1 (0.66) | KDM4EHTR6HTR1ADRD2DRD4 | |
| SCHEMBL7616574 | 0.83 | KMT2A (0.52) | KDM4EHTR6HTR1ADRD2DRD4 | |
| SCHEMBL8472324 | 0.82 | MEN1 (0.53) | KDM4EHTR6HTR1ADRD2DRD4 | |
| SCHEMBL3030210 | 0.81 | KDM4E (0.62) | KDM4EHTR6HTR1ADRD2DRD4 | |
| SCHEMBL8472895 | 0.80 | HTR6 (0.55) | KDM4EHTR6HTR1ADRD2DRD4 | |
| SCHEMBL6014782 | 0.80 | MEN1 (0.61) | KDM4EHTR6HTR1ADRD2DRD4 | |
| SCHEMBL7679486 | 0.79 | ALDH1A1 (0.60) | KDM4EHTR6HTR1ADRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |