Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | NPY1R | P25929 | 2/20 | 0.43 |
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CCR5 | P51681 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | GPR88 | Q9GZN0 | 2/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477090 | 0.92 | NPY1R (0.40) | NPY1RLTA4HHTTKDM4ESMN1; SMN2 | |
| SCHEMBL8477078 | 0.91 | HTR2C (0.42) | HTR2CHTR2BNPY1RLTA4HKDM4E | |
| SCHEMBL8474898 | 0.91 | EGFR (0.40) | HTR2CHTR2BNPY1RCCR5L3MBTL1 | |
| SCHEMBL8901044 | 0.90 | NPY1R (0.41) | NPY1RLTA4HHTTKDM4ESMN1; SMN2 | |
| SCHEMBL8472629 | 0.89 | CACNA2D1 (0.40) | NPY1RKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8479145 | 0.89 | HTR2C (0.42) | HTR2CHTR2BNPY1RNPC1RAB9A | |
| SCHEMBL8475106 | 0.85 | HTR6 (0.41) | HTTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8474453 | 0.85 | LMNA (0.49) | HTR2CHTR2BKDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8472006 | 0.84 | HTT (0.52) | NPY1RLTA4HHTTKDM4ENPC1 | |
| SCHEMBL8472339 | 0.83 | SMN1; SMN2 (0.40) | HTR2CHTR2BKDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |