Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | NPY1R | P25929 | 1/20 | 0.49 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.45 |
| ▸ | MCHR2 | Q969V1 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477094 | 0.90 | LTA4H (0.58) | HTTKDM4ESMN1; SMN2ALDH1A1L3MBTL1 | |
| SCHEMBL8477079 | 0.90 | HTT (0.48) | HTTRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL8474896 | 0.89 | EGFR (0.47) | HTTRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL8472630 | 0.88 | POLB (0.45) | RAB9AKDM4EALDH1A1 | |
| SCHEMBL8475983 | 0.88 | LTA4H (0.50) | HTTRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL8479146 | 0.87 | HTT (0.45) | HTTRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL8472363 | 0.87 | POLB (0.47) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8472891 | 0.85 | EGFR (0.45) | EGFRLTA4H | |
| SCHEMBL8474454 | 0.84 | LMNA (0.53) | HTTRAB9ANPC1KDM4ESMN1; SMN2 | |
| SCHEMBL8472003 | 0.84 | HTR2C (0.43) | HTTRAB9ANPC1KDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |