Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 2/20 | 0.45 |
| ▸ | HTR7 | P34969 | 4/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472630 | 0.99 | POLB (0.45) | POLBKDM4EGLAALDH1A1PLK1 | |
| SCHEMBL8477333 | 0.93 | HTR7 (0.48) | POLBKDM4EGLAHTR7CNR2 | |
| SCHEMBL8477838 | 0.93 | CNR2 (0.48) | POLBKDM4EGLAALDH1A1HTR7 | |
| SCHEMBL8472201 | 0.92 | KDM4E (0.47) | POLBKDM4EGLAALDH1A1PLK1 | |
| SCHEMBL8475107 | 0.91 | KDM4E (0.45) | POLBKDM4EGLAALDH1A1PLK1 | |
| SCHEMBL8474442 | 0.89 | ATM (0.50) | POLBKDM4EALDH1A1CNR2ALOX15 | |
| SCHEMBL8477094 | 0.88 | LTA4H (0.58) | KDM4EALDH1A1LMNA | |
| SCHEMBL8472006 | 0.87 | HTT (0.52) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL8477346 | 0.87 | KDM4E (0.45) | KDM4EALDH1A1CNR2LMNA | |
| SCHEMBL8475956 | 0.87 | KDM4E (0.54) | POLBKDM4EALDH1A1LMNAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |