Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 8/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | FABP4 | P15090 | 1/20 | 0.42 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477838 | 0.98 | CNR2 (0.48) | HTR7CNR2ABCB1POLBKDM4E | |
| SCHEMBL8472630 | 0.94 | POLB (0.45) | HTR7POLBKDM4EGLA | |
| SCHEMBL8472363 | 0.93 | POLB (0.47) | HTR7CNR2POLBKDM4EGLA | |
| SCHEMBL8472860 | 0.87 | HTR7 (0.43) | HTR7CNR2POLBKDM4E | |
| SCHEMBL8475107 | 0.86 | KDM4E (0.45) | POLBKDM4EGLA | |
| SCHEMBL8474648 | 0.86 | PTGER4 (0.48) | HTR7CNR2ABCB1KDM4E | |
| SCHEMBL8472201 | 0.85 | KDM4E (0.47) | ABCB1POLBKDM4EGLA | |
| SCHEMBL8898545 | 0.85 | CNR2 (0.44) | HTR7CNR2ABCB1POLBKDM4E | |
| SCHEMBL8474442 | 0.85 | ATM (0.50) | CNR2POLBKDM4E | |
| SCHEMBL8475739 | 0.85 | KDM4E (0.48) | HTR7CNR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |