Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | GLA | P06280 | 1/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | HTR6 | P50406 | 4/20 | 0.59 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | DRD4 | P21917 | 1/20 | 0.55 |
| ▸ | DRD3 | P35462 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DOCK5 | Q9H7D0 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5961922 | 0.84 | LMNA (0.69) | LMNAGLAALDH1A1TSHRHTR6 | |
| SCHEMBL14375226 | 0.81 | LMNA (0.64) | LMNAGLAALDH1A1TSHRSLC6A4 | |
| SCHEMBL2162689 | 0.79 | LMNA (1.00) | LMNAGLAALDH1A1TSHRGPR84 | |
| Hydrochloric Acid SCHEMBL28233643 | 0.77 | HTR7 (0.60) | LMNAGLAHTR6 | |
| Hydrochloric Acid SCHEMBL28233646 | 0.77 | HTR7 (0.61) | LMNAHTR6 | |
| SCHEMBL28780669 | 0.76 | SLC6A4 (0.75) | LMNAGLAALDH1A1TSHRSLC6A4 | |
| SCHEMBL5196972 | 0.75 | LMNA (0.81) | LMNAGLAALDH1A1TSHRHTR6 | |
| SCHEMBL947747 | 0.74 | HTR6 (1.00) | HTR6 | |
| SCHEMBL15084330 | 0.73 | LMNA (0.55) | LMNAGLAALDH1A1TSHRGPR84 | |
| SCHEMBL5881100 | 0.73 | GPR84 (1.00) | LMNAGLAALDH1A1TSHRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889032-A | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-03-30 | — | — | US | disclosed |