Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.52 |
| ▸ | CA9 | Q16790 | 15/20 | 0.52 |
| ▸ | CA1 | P00915 | 12/20 | 0.52 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | PTGES2 | Q9H7Z7 | 2/20 | 0.48 |
| ▸ | IKBKB | O14920 | 2/20 | 0.46 |
| ▸ | CHUK | O15111 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biphenyl SCHEMBL2902198 | 0.83 | PTGES2 (0.54) | CA2CA9CA1CA12CA14 | |
| SCHEMBL12294066 | 0.78 | TSHR (0.55) | — | |
| SCHEMBL21973519 | 0.78 | TSHR (0.55) | — | |
| SCHEMBL8481494 | 0.77 | CA2 (0.57) | CA2CA9CA1CA12CA14 | |
| SCHEMBL7188667 | 0.77 | PTGES2 (0.64) | CA2CA9CA1CA12CA14 | |
| SCHEMBL6168875 | 0.77 | CA2 (0.68) | CA2CA9CA1CA12CA14 | |
| SCHEMBL8475151 | 0.74 | CA2 (0.57) | CA2CA9CA1CA12CA14 | |
| SCHEMBL5698111 | 0.73 | TSHR (0.60) | — | |
| SCHEMBL185757 | 0.73 | CA2 (0.61) | CA2CA9CA1CA12CA14 | |
| SCHEMBL3949466 | 0.73 | CA2 (0.53) | CA2CA9CA1CA12CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859257-A | ANTIINFLAMMATORY, ANTIARTHRITIC AGENTS | G. D. SEARLE & CO. (US) | 1999-01-12 | — | — | US | disclosed |