Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 1/20 | 0.50 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7364364 | 0.78 | DRD4 (0.59) | MAPTTSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL7360171 | 0.78 | ADRB1 (0.43) | LMNA | |
| SCHEMBL6773141 | 0.78 | MAPT (0.52) | MAPTTSHRMAPK1SMN1; SMN2HPGD | |
| SCHEMBL8476801 | 0.78 | MAPK1 (0.58) | MAPTMAPK1LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL3137445 | 0.77 | MAPT (0.53) | MAPTTSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL4541604 | 0.76 | DRD4 (0.57) | MAPTTSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL3134694 | 0.74 | ALDH1A1 (0.63) | MAPTTSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL4653292 | 0.74 | MAPT (0.66) | MAPTTSHRMAPK1LMNASMN1; SMN2 | |
| SCHEMBL7388920 | 0.74 | ALDH1A1 (0.65) | MAPTTSHRLMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL1107020 | 0.74 | CHRNB2 (0.46) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5994356-A | ANTICOAGULANT | KARL THOMAE (DE) | 1999-11-30 | — | — | US | disclosed |