Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | HEXA | P06865 | 1/20 | 0.31 |
| ▸ | HEXB | P07686 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475225 | 0.88 | MAPT (0.44) | NPC1RAB9AKDM4EMAPTGAA | |
| SCHEMBL8477183 | 0.87 | MAPT (0.36) | NPC1RAB9AALDH1A1KDM4EHSD17B10 | |
| SCHEMBL8474965 | 0.81 | ALDH1A1 (0.37) | NPC1RAB9AALDH1A1KDM4ETP53 | |
| SCHEMBL8480185 | 0.79 | HEXA (0.42) | NPC1RAB9AALDH1A1KDM4ETP53 | |
| SCHEMBL8478757 | 0.77 | MAPT (0.44) | NPC1RAB9AKMT2AMAPTGAA | |
| SCHEMBL8474655 | 0.76 | HEXA (0.42) | NPC1RAB9AALDH1A1HSD17B10MAPT | |
| SCHEMBL8478542 | 0.75 | PTGS2 (0.47) | KMT2AMAPTGAAHEXAHEXB | |
| SCHEMBL8474322 | 0.74 | MAPT (0.37) | NPC1RAB9AALDH1A1KDM4ETP53 | |
| SCHEMBL8480049 | 0.73 | PDE4B (0.36) | NPC1RAB9AHSD17B10KMT2AMAPT | |
| SCHEMBL8474614 | 0.72 | HEXA (0.46) | NPC1RAB9AKDM4EMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |