Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HEXA | P06865 | 2/20 | 0.42 |
| ▸ | HEXB | P07686 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | DPP4 | P27487 | 6/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GCGR | P47871 | 2/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | USP7 | Q93009 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8480104 | 0.88 | HEXA (0.40) | HEXAHEXBALDH1A1KDM4ENPC1 | |
| SCHEMBL8474614 | 0.84 | HEXA (0.46) | HEXAHEXBKDM4ENPC1RAB9A | |
| SCHEMBL8474672 | 0.79 | NPC1 (0.34) | HEXAHEXBALDH1A1KDM4ENPC1 | |
| SCHEMBL8478772 | 0.71 | BRD4 (0.36) | ALDH1A1KDM4ENPC1RAB9ATP53 | |
| SCHEMBL8478757 | 0.70 | MAPT (0.44) | HEXAHEXBNPC1RAB9AGAA | |
| SCHEMBL8478069 | 0.67 | HEXA (0.44) | HEXAHEXBALDH1A1KDM4ENPC1 | |
| SCHEMBL8477183 | 0.65 | MAPT (0.36) | ALDH1A1KDM4ENPC1RAB9AHSD17B10 | |
| SCHEMBL8480167 | 0.65 | ALDH1A1 (0.33) | HEXAHEXBALDH1A1DPP4SMN1; SMN2 | |
| SCHEMBL8478421 | 0.65 | ALDH1A1 (0.36) | HEXAHEXBALDH1A1DPP4SMN1; SMN2 | |
| SCHEMBL8476218 | 0.64 | GCGR (0.33) | HEXAHEXBALDH1A1DPP4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |