Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479871 | 0.84 | MAPT (0.40) | PTGS2ALDH1A1HPGDRAB9ANPC1 | |
| SCHEMBL8480173 | 0.84 | PTGS2 (0.44) | PTGS2HPGDCA12CA1CA2 | |
| SCHEMBL8474956 | 0.78 | KDM4E (0.40) | PTGS2ALDH1A1RAB9ANPC1KMT2A | |
| SCHEMBL8475225 | 0.76 | MAPT (0.44) | PTGS2RAB9ANPC1ESR2POLB | |
| SCHEMBL20323072 | 0.70 | CA1 (0.69) | PTGS2ALDH1A1CA12CA1CA2 | |
| SCHEMBL8474672 | 0.67 | NPC1 (0.34) | ALDH1A1RAB9ANPC1KMT2AGAA | |
| SCHEMBL6816552 | 0.67 | PTGS2 (0.40) | PTGS2ALDH1A1HPGDCA12CA1 | |
| SCHEMBL8475285 | 0.67 | PTGS2 (0.40) | PTGS2ALDH1A1HPGDCA12CA1 | |
| SCHEMBL15696254 | 0.66 | PTGS2 (0.50) | PTGS2HPGDCA12CA1CA2 | |
| SCHEMBL8474308 | 0.66 | POLB (0.43) | PTGS2HPGDRAB9ANPC1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |