SCHEMBL8475248

SCHEMBL8475248

CCCc1[c]cc(-c2ccc(C)cc2)c(-c2ccc(C)cc2)c1OC

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MGAM O43451 6/20 0.33
GAA P10253 6/20 0.33
SI P14410 6/20 0.33
MGAM2 Q2M2H8 6/20 0.33
GCGR P47871 1/20 0.31
ALDH1A1 P00352 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8479825 0.88 USP7 (0.33) MGAMGAASIMGAM2ALDH1A1
SCHEMBL8476328 0.87 PDE4B (0.40) MGAMGAASIMGAM2GCGR
SCHEMBL8476218 0.82 GCGR (0.33) GAAGCGRALDH1A1
SCHEMBL8479875 0.79 MGAM (0.34) MGAMGAASIMGAM2ALDH1A1
SCHEMBL8479699 0.77 HEXA (0.38) MGAMGAASIMGAM2
SCHEMBL8482102 0.75 GCGR (0.32) GAAGCGRALDH1A1
SCHEMBL8477677 0.75 PDE4B (0.43) MGAMGAASIMGAM2ALDH1A1
SCHEMBL8477540 0.75 PDE4B (0.42) MGAMGAASIMGAM2GCGR
SCHEMBL8479901 0.74
SCHEMBL8476983 0.73 GAA (0.40) MGAMGAASIMGAM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6004988-A Carboxylic acid derivatives, their preparation and their use BASF AKTIENGESELLSCHAFT (DE) 1999-12-21 US disclosed