Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 4/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | BCR | P11274 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8479756 | 0.85 | HEXA (0.38) | PTGS2HDAC4HDAC2HDAC8POLB | |
| SCHEMBL8477304 | 0.82 | PDCD1 (0.38) | HDAC4HDAC2HDAC8MEN1KMT2A | |
| SCHEMBL8477928 | 0.80 | PTGS2 (0.38) | PTGS2 | |
| SCHEMBL8480091 | 0.77 | PTGS2 (0.47) | PTGS2HDAC4HDAC2HDAC8MEN1 | |
| SCHEMBL8475444 | 0.77 | LTA4H (0.41) | PTGS2HDAC4HDAC2HDAC8MEN1 | |
| SCHEMBL8480981 | 0.77 | PTGS2 (0.46) | PTGS2HDAC4HDAC2HDAC8MEN1 | |
| SCHEMBL8474577 | 0.74 | MGAM (0.46) | MEN1KMT2AGAAABCB1BACE1 | |
| SCHEMBL8479699 | 0.74 | HEXA (0.38) | PTGS2HDAC4HDAC2HDAC8POLB | |
| SCHEMBL8476218 | 0.73 | GCGR (0.33) | GAASMN1; SMN2LMNA | |
| SCHEMBL8477677 | 0.72 | PDE4B (0.43) | PTGS2GAABACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |