SCHEMBL7014947

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7010267	0.87	LMNA (0.61)	EGLN1HPGDLMNAALDH1A1POLB
	SCHEMBL4072045	0.85	KDM4E (0.59)	EGLN1HPGDLMNAHDAC3HDAC4
	SCHEMBL7014944	0.83	RAB9A (0.58)	EGLN1RAB9AHPGDSMN1; SMN2LMNA
	SCHEMBL7014023	0.83	ALDH1A1 (0.59)	HPGDSMN1; SMN2ALDH1A1POLBMEN1
	SCHEMBL7013264	0.83	EGLN1 (0.48)	EGLN1LMNAHDAC3HDAC4HDAC1
	SCHEMBL7018465	0.82	EGLN1 (0.59)	EGLN1RAB9AHPGDSMN1; SMN2LMNA
	SCHEMBL7016470	0.80	MEN1 (0.71)	HPGDSMN1; SMN2LMNAHDAC1ALDH1A1
	SCHEMBL27962856	0.80	RAB9A (0.70)	EGLN1RAB9AHPGDSMN1; SMN2LMNA
	SCHEMBL616897	0.78	EGLN1 (0.60)	EGLN1RAB9AHPGDSMN1; SMN2LMNA
	SCHEMBL2201315	0.78	EGLN1 (1.00)	EGLN1HPGDSMN1; SMN2LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.