Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G2A | P14555 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472891 | 0.90 | EGFR (0.45) | LTA4HMAPT | |
| SCHEMBL8476671 | 0.90 | KMT2A (0.47) | PLA2G2AKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL8475096 | 0.90 | KDM4E (0.39) | KDM4EPOLBALDH1A1LTA4HPPARG | |
| SCHEMBL8477366 | 0.89 | ALDH1A1 (0.47) | PLA2G2AKDM4EPOLBALDH1A1MAPT | |
| SCHEMBL7612724 | 0.89 | ALDH1A1 (0.39) | PLA2G2AKDM4EPOLBALDH1A1KMT2A | |
| SCHEMBL8476437 | 0.87 | KDM4E (0.39) | PLA2G2AKDM4EPOLBALDH1A1PPARG | |
| SCHEMBL8478179 | 0.85 | HTR6 (0.44) | PLA2G2AKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL8472303 | 0.84 | POLB (0.43) | PLA2G2AKDM4EPOLBALDH1A1MEN1 | |
| SCHEMBL8471927 | 0.84 | UTS2R (0.45) | PLA2G2AKDM4EPOLBALDH1A1MEN1 | |
| Hydrochloric Acid SCHEMBL8477102 | 0.84 | SMN1; SMN2 (0.40) | KDM4EALDH1A1KMT2APPARGLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |