Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | TOP2A | P11388 | 1/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478179 | 0.93 | HTR6 (0.44) | ALDH1A1POLBCYP1A2HTR6KDM4E | |
| SCHEMBL8474419 | 0.93 | CHRM2 (0.46) | ALDH1A1POLBCYP1A2HTR6KDM4E | |
| SCHEMBL8471927 | 0.92 | UTS2R (0.45) | ALDH1A1POLBCYP1A2HTR6KDM4E | |
| SCHEMBL8472303 | 0.92 | POLB (0.43) | ALDH1A1POLBCYP1A2HTR6KDM4E | |
| SCHEMBL8477212 | 0.92 | TOP2A (0.46) | HTR6KDM4EMAPTTOP2ACNR2 | |
| SCHEMBL8475829 | 0.89 | PLA2G2A (0.42) | ALDH1A1POLBCYP1A2KDM4EMAPT | |
| SCHEMBL8477506 | 0.88 | HTR6 (0.41) | ALDH1A1POLBCYP1A2HTR6KDM4E | |
| SCHEMBL8472891 | 0.88 | EGFR (0.45) | MAPT | |
| SCHEMBL8476849 | 0.87 | OPRD1 (0.44) | ALDH1A1POLBCYP1A2HTR6PTGER4 | |
| Hydrochloric Acid SCHEMBL8475839 | 0.87 | PTGER4 (0.44) | ALDH1A1POLBCYP1A2HTR6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |