Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474563 | 0.94 | LTA4H (0.50) | HRH3KCNH2PTGER4LTA4HESR1 | |
| SCHEMBL8475983 | 0.89 | LTA4H (0.50) | HRH3KCNH2LTA4HESR1SMN1; SMN2 | |
| SCHEMBL8473765 | 0.89 | PTGER4 (0.52) | PTGER4SMN1; SMN2KDM4EALDH1A1HPGD | |
| SCHEMBL8474896 | 0.89 | EGFR (0.47) | PTGER4LTA4HSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL8475515 | 0.88 | PTGER4 (0.51) | HRH3KCNH2PTGER4SMN1; SMN2KDM4E | |
| SCHEMBL8472573 | 0.87 | KMT2A (0.44) | PTGER4HPGD | |
| SCHEMBL8475897 | 0.86 | NPY1R (0.38) | SMN1; SMN2KDM4EALDH1A1LMNATP53 | |
| SCHEMBL8477374 | 0.86 | PTGER4 (0.51) | PTGER4SMN1; SMN2KDM4EALDH1A1LMNA | |
| SCHEMBL8477133 | 0.85 | PTGER4 (0.48) | HRH3KCNH2PTGER4KDM4EALDH1A1 | |
| SCHEMBL8475375 | 0.85 | PTGER4 (0.50) | PTGER4SMN1; SMN2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |